Literature DB >> 14148430

HOMOCITRULLINE AND HOMOARGININE SYNTHESIS FROM LYSINE.

W L RYAN, I C WELLS.   

Abstract

After the injection of L-lysine and uniformly labeled L-lysine-carbon-14 into the rat, labeled homocitrulline and homoarginine are found in the liver and kidney. The ingestion of lysine by seven normal adults results in an increased urinary excretion of homocitrulline and homoarginine. These data suggest the occurrence of an unreported metabolic pathway for lysine in the rat and man.

Entities:  

Keywords:  AMINO ACIDS; CARBON ISOTOPES; CHROMATOGRAPHY; EXPERIMENTAL LAB STUDY; KIDNEY; LIVER; LYSINE; PROTEIN METABOLISM; RATS; URINE

Mesh：

Substances：

Year:  1964        PMID： 14148430     DOI： 10.1126/science.144.3622.1122

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  16 in total

1.  Dietary L-lysine prevents arterial calcification in adenine-induced uremic rats.

Authors:  Akihiro Shimomura; Isao Matsui; Takayuki Hamano; Takuya Ishimoto; Yumiko Katou; Kenji Takehana; Kazunori Inoue; Yasuo Kusunoki; Daisuke Mori; Chikako Nakano; Yoshitsugu Obi; Naohiko Fujii; Yoshitsugu Takabatake; Takayoshi Nakano; Yoshiharu Tsubakihara; Yoshitaka Isaka; Hiromi Rakugi
Journal:  J Am Soc Nephrol       Date:  2014-03-20       Impact factor: 10.121

2.  Associations of homoarginine with bone metabolism and density, muscle strength and mortality: cross-sectional and prospective data from 506 female nursing home patients.

Authors:  S Pilz; A Meinitzer; A Tomaschitz; K Kienreich; H Dobnig; M Schwarz; D Wagner; C Drechsler; C Piswanger-Sölkner; W März; A Fahrleitner-Pammer
Journal:  Osteoporos Int       Date:  2012-03-17       Impact factor: 4.507

3.  Hyperpipecolatemia: A new metabolic disorder associated with neuropathy and hepatomegaly: A case study.

Authors:  P D Gatfield; E Taller; G G Hinton; A C Wallace; G M Abdelnour; M D Haust
Journal:  Can Med Assoc J       Date:  1968-12-28       Impact factor: 8.262

4.  Amino acid patterns in cystinuric families.

Authors:  S Kelly; W Copeland
Journal:  J Med Genet       Date:  1968-12       Impact factor: 6.318

5.  [Thin-layer chromatography of acid-and ether-soluble dinitrophenyl amino acids in the urine].

Authors:  W Bürgi; J P Colombo; R Richterich
Journal:  Klin Wochenschr       Date:  1965-11-15

6.  Familial hyperargininaemia.

Authors:  H G Terheggen; A Lowenthal; F Lavinha; J P Colombo
Journal:  Arch Dis Child       Date:  1975-01       Impact factor: 3.791

7.  Metabolically stable apelin-analogues, incorporating cyclohexylalanine and homoarginine, as potent apelin receptor activators.

Authors:  Kleinberg X Fernandez; Conrad Fischer; Jennie Vu; Mahmoud Gheblawi; Wang Wang; Samantha Gottschalk; Xavier Iturrioz; Catherine Llorens-Cortés; Gavin Y Oudit; John C Vederas
Journal:  RSC Med Chem       Date:  2021-07-08

8.  Ketogenic diets slow melanoma growth in vivo regardless of tumor genetics and metabolic plasticity.

Authors:  Daniela D Weber; Sepideh Aminzadeh-Gohari; Maheshwor Thapa; Anna-Sophia Redtenbacher; Luca Catalano; Tânia Capelôa; Thibaut Vazeille; Michael Emberger; Thomas K Felder; René G Feichtinger; Peter Koelblinger; Guido Dallmann; Pierre Sonveaux; Roland Lang; Barbara Kofler
Journal:  Cancer Metab       Date:  2022-07-18

9.  Homoarginine, heart failure, and sudden cardiac death in haemodialysis patients.

Authors:  Christiane Drechsler; Andreas Meinitzer; Stefan Pilz; Vera Krane; Andreas Tomaschitz; Eberhard Ritz; Winfried März; Christoph Wanner
Journal:  Eur J Heart Fail       Date:  2011-08       Impact factor: 15.534

10.  Homoarginine and progression of chronic kidney disease: results from the Mild to Moderate Kidney Disease Study.

Authors:  Christiane Drechsler; Barbara Kollerits; Andreas Meinitzer; Winfried März; Eberhard Ritz; Paul König; Ulrich Neyer; Stefan Pilz; Christoph Wanner; Florian Kronenberg
Journal:  PLoS One       Date:  2013-05-15       Impact factor: 3.240
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