PURPOSE AND METHODS: High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years. FINDINGS: For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009). CONCLUSIONS: This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.
PURPOSE AND METHODS: High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years. FINDINGS: For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009). CONCLUSIONS: This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.
Authors: Frank P MacMaster; Matcheri Keshavan; Yousha Mirza; Normand Carrey; Ameet R Upadhyaya; Rhonda El-Sheikh; Christian J Buhagiar; S Preeya Taormina; Courtney Boyd; Michelle Lynch; Michelle Rose; Jennifer Ivey; Gregory J Moore; David R Rosenberg Journal: Life Sci Date: 2006-11-29 Impact factor: 5.037
Authors: F Romo-Nava; W S Hoogenboom; P E Pelavin; J L Alvarado; L H Bobrow; F P Macmaster; M Keshavan; R W McCarley; M E Shenton Journal: Schizophr Res Date: 2013-03-19 Impact factor: 4.939
Authors: Eileen M Moore; M Alejandra Infante; Robyn Migliorini; Sarah N Mattson; Edward P Riley Journal: Neurotoxicol Teratol Date: 2016-09-09 Impact factor: 3.763
Authors: D Kiortsis; V Xydis; A G Drougia; P I Argyropoulou; S Andronikou; S C Efremidis; M I Argyropoulou Journal: Neuroradiology Date: 2004-02-21 Impact factor: 2.804