Literature DB >> 1414666

Association of age with regional cerebral oxygen utilization: a positron emission tomography study.

A Burns1, P Tyrrell.   

Abstract

Positron emission tomography scans were performed on 14 normal subjects over the age of 50. Cerebral metabolic rate for oxygen (CMRO2) was assessed in a number of cortical and subcortical regions. There was a trend for a decrease in CMRO2 with age but this was significant only in the parietal lobe. There was a suggestion that the age/CMRO2 correlation became less strong with advancing age. CMRO2 in the occipital lobe, subcortical regions and cerebellum was not related to age. The relationship between CMRO2 and age is discussed.

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Year:  1992        PMID： 1414666     DOI： 10.1093/ageing/21.5.316

Source DB:  PubMed          Journal:  Age Ageing        ISSN： 0002-0729            Impact factor:   10.668


  7 in total

1.  Brain energy metabolism and blood flow differences in healthy aging.

Authors:  Joel Aanerud; Per Borghammer; M Mallar Chakravarty; Kim Vang; Anders B Rodell; Kristjana Y Jónsdottir; Arne Møller; Mahmoud Ashkanian; Manouchehr S Vafaee; Peter Iversen; Peter Johannsen; Albert Gjedde
Journal:  J Cereb Blood Flow Metab       Date:  2012-02-29       Impact factor: 6.200

2.  Neural correlates of pair-bonding in a monogamous primate.

Authors:  Karen L Bales; William A Mason; Ciprian Catana; Simon R Cherry; Sally P Mendoza
Journal:  Brain Res       Date:  2007-10-11       Impact factor: 3.252

3.  Aerobic glycolysis in the human brain is associated with development and neotenous gene expression.

Authors:  Manu S Goyal; Michael Hawrylycz; Jeremy A Miller; Abraham Z Snyder; Marcus E Raichle
Journal:  Cell Metab       Date:  2014-01-07       Impact factor: 27.287

Review 4.  The impact of age on cerebral perfusion, oxygenation and metabolism during exercise in humans.

Authors:  Igor D Braz; James P Fisher
Journal:  J Physiol       Date:  2015-11-02       Impact factor: 5.182

5.  Age-associated reductions in cerebral blood flow are independent from regional atrophy.

Authors:  J Jean Chen; H Diana Rosas; David H Salat
Journal:  Neuroimage       Date:  2010-12-16       Impact factor: 6.556

6.  Compromised microvascular oxygen delivery increases brain tissue vulnerability with age.

Authors:  Mohammad Moeini; Xuecong Lu; Pramod K Avti; Rafat Damseh; Samuel Bélanger; Frédéric Picard; David Boas; Ashok Kakkar; Frédéric Lesage
Journal:  Sci Rep       Date:  2018-05-29       Impact factor: 4.379

7.  An investigation of cerebral oxygen utilization, blood flow and cognition in healthy aging.

Authors:  Sarah J Catchlove; Helen Macpherson; Matthew E Hughes; Yufen Chen; Todd B Parrish; Andrew Pipingas
Journal:  PLoS One       Date:  2018-05-22       Impact factor: 3.240
  7 in total

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