Literature DB >> 1414093

Distribution of ASFV antigens in pig tissues experimentally infected with two different Spanish virus isolates.

A Fernandez1, J Perez, L Carrasco, M J Bautista, J M Sanchez-Vizcaino, M A Sierra.   

Abstract

Lymph nodes, spleen, liver, lung and kidney obtained from pigs experimentally infected with two African Swine Fever Virus (ASFV) isolates of differing virulence were fixed by perfusion with glutaraldehyde and embedded in paraffin. An immunoperoxidase technique using a polyclonal anti-ASFV serum was performed on tissue sections in order to detect ASFV antigen. The distribution of ASFV antigen in such infected organs is shown and the differences between both infections compared and discussed. Monocytes, macrophages, hepatocytes, endothelial cells, neutrophils and epithelial cells were found to contain ASFV antigens.

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Year:  1992        PMID： 1414093     DOI： 10.1111/j.1439-0450.1992.tb01187.x

Source DB:  PubMed          Journal:  Zentralbl Veterinarmed B        ISSN： 0514-7166


  5 in total

1.  Ultrastructural study of the renal tubular system in acute experimental African swine fever: virus replication in glomerular mesangial cells and in the collecting ducts.

Authors:  J C Gómez-Villamandos; J Hervás; A Méndez; L Carrasco; C J Villeda; P J Wilkinson; M A Sierra
Journal:  Arch Virol       Date:  1995       Impact factor: 2.574

Review 2.  The lesional changes and pathogenesis in the kidney in African swine fever.

Authors:  J Hervás; J C Gómez-Villamandos; A Méndez; L Carrasco; M A Sierra
Journal:  Vet Res Commun       Date:  1996       Impact factor: 2.459

3.  Macrophage transcriptional responses following in vitro infection with a highly virulent African swine fever virus isolate.

Authors:  Fuquan Zhang; Paul Hopwood; Charles C Abrams; Alison Downing; Frazer Murray; Richard Talbot; Alan Archibald; Stewart Lowden; Linda K Dixon
Journal:  J Virol       Date:  2006-11       Impact factor: 5.103

4.  African Swine Fever Laboratory Diagnosis-Lessons Learned from Recent Animal Trials.

Authors:  Jutta Pikalo; Paul Deutschmann; Melina Fischer; Hanna Roszyk; Martin Beer; Sandra Blome
Journal:  Pathogens       Date:  2021-02-06

5.  African swine fever virus AP endonuclease is a redox-sensitive enzyme that repairs alkylating and oxidative damage to DNA.

Authors:  Modesto Redrejo-Rodríguez; Alexander A Ishchenko; Murat K Saparbaev; María L Salas; José Salas
Journal:  Virology       Date:  2009-05-22       Impact factor: 3.616
  5 in total

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