Literature DB >> 14140

Decreased lysyl oxidase activity in the aneurysm-prone, mottled mouse.

D W Rowe, E B McGoodwin, G R Martin, D Grahn.   

Abstract

Inbred mice bearing certain alleles at the Mottled locus have defects in connective tissue which result in weakness of skin and of blood vessels. Previous studies have established that cross-links in collagen and elastin are decreased in these animals due to impaired formation of lysine-derived aldehydes. Lysyl oxidase activity in extracts of skin is markedly lower in those prepared from affected animals than control mice. An inhibitor of lysyl oxidase is present in equal amounts in affected and control skins and does not account for diminished activity found in affected animals.

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Year:  1977        PMID： 14140

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  26 in total

Review 1.  Lessons from Animal Models of Arterial Aneurysm.

Authors:  S David Gertz; Yoav Mintz; Ronen Beeri; Chen Rubinstein; Dan Gilon; Leah Gavish; Yacov Berlatzky; Liat Appelbaum; Lilach Gavish
Journal:  Aorta (Stamford)       Date:  2013-10-01

2.  Experimental cerebral aneurysms in the female heterozygous Blotchy mouse.

Authors:  M Coutard
Journal:  Int J Exp Pathol       Date:  1999-12       Impact factor: 1.925

3.  The lung of the copper-deficient rat. A model for developmental pulmonary emphysema.

Authors:  B L O'Dell; K H Kilburn; W N McKenzie; R J Thurston
Journal:  Am J Pathol       Date:  1978-06       Impact factor: 4.307

4.  Copper Transporter ATP7A (Copper-Transporting P-Type ATPase/Menkes ATPase) Limits Vascular Inflammation and Aortic Aneurysm Development: Role of MicroRNA-125b.

Authors:  Varadarajan Sudhahar; Archita Das; Tetsuo Horimatsu; Dipankar Ash; Silvia Leanhart; Olga Antipova; Stefan Vogt; Bhupesh Singla; Gabor Csanyi; Joseph White; Jack H Kaplan; David Fulton; Neal L Weintraub; Ha Won Kim; Masuko Ushio-Fukai; Tohru Fukai
Journal:  Arterioscler Thromb Vasc Biol       Date:  2019-09-26       Impact factor: 8.311

5.  Type IX Ehlers-Danlos syndrome and Menkes syndrome: the decrease in lysyl oxidase activity is associated with a corresponding deficiency in the enzyme protein.

Authors:  H Kuivaniemi; L Peltonen; K I Kivirikko
Journal:  Am J Hum Genet       Date:  1985-07       Impact factor: 11.025

6.  Upregulation of protein kinase cdelta in vascular smooth muscle cells promotes inflammation in abdominal aortic aneurysm.

Authors:  Sebastian Schubl; Shirling Tsai; Evan J Ryer; Chunjie Wang; June Hu; K Craig Kent; Bo Liu
Journal:  J Surg Res       Date:  2008-05-13       Impact factor: 2.192

7.  Marfan syndrome: abnormal alpha 2 chain in type I collagen.

Authors:  P H Byers; R C Siegel; K E Peterson; D W Rowe; K A Holbrook; L T Smith; Y H Chang; J C Fu
Journal:  Proc Natl Acad Sci U S A       Date:  1981-12       Impact factor: 11.205

8.  Copper metabolism in mottled mouse mutants. The effect of copper therapy on lysyl oxidase activity in brindled (Mobr) mice.

Authors:  P M Royce; J Camakaris; J R Mann; D M Danks
Journal:  Biochem J       Date:  1982-02-15       Impact factor: 3.857

9.  Abnormal copper metabolism and deficient lysyl oxidase activity in a heritable connective tissue disorder.

Authors:  H Kuivaniemi; L Peltonen; A Palotie; I Kaitila; K I Kivirikko
Journal:  J Clin Invest       Date:  1982-03       Impact factor: 14.808

10.  Metallothionein and the development of the mottled disorder in the mouse.

Authors:  D M Hunt; R Clarke
Journal:  Biochem Genet       Date:  1983-12       Impact factor: 1.890
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