Literature DB >> 14132169

CLINICAL STUDIES UTILIZING A NEW METHOD FOR THE SERIAL DETERMINATION OF PLASMA CORTICOIDS.

B E MURPHY, A B HOOD, C J PATTEE.   

Abstract

The clinical applications of a recently introduced method for determination of plasma corticoids were investigated with a view to its routine use in the evaluation of pituitary-adrenal problems. Simple protocols to assess the diurnal variation and the responses of the plasma corticoids to adrenocorticotropin, dexamethasone, and methopyrapone administration were adopted to study healthy subjects, chronically ill subjects free of endocrine disease, and subjects with previously diagnosed adrenal or pituitary disorders. The results in all cases were in accord with the clinical assessment of the subjects.

Entities:  

Keywords:  ADRENAL CORTEX HORMONES; ADRENAL GLAND DISEASES; ALDOSTERONE ANTAGONISTS; BLOOD CHEMICAL ANALYSIS; CANADA; CORTICOTROPIN; DEXAMETHASONE; METYRAPONE

Mesh：

Substances：

Year:  1964        PMID： 14132169      PMCID： PMC1922543     

Source DB:  PubMed          Journal:  Can Med Assoc J        ISSN： 0008-4409            Impact factor:   8.262


  8 in total

1.  The effect of intravenously-administered ACTH on plasma 17,21-dihydroxy-20-ketosteroids in normal individuals and in patients with disorders of the adrenal cortex.

Authors:  N P CHRISTY; E Z WALLACE; J W JAILER
Journal:  J Clin Invest       Date:  1955-06       Impact factor: 14.808

2.  Simple method for the determination of plasma corticoids.

Authors:  B P MURPHY; W ENGELBERG; C J PATTEE
Journal:  J Clin Endocrinol Metab       Date:  1963-03       Impact factor: 5.958

3.  Quantitation of pituitary corticotropin reserve in man by use of an adrenocortical 11-beta hydroxylase inhibitor (SU-4885).

Authors:  E M GOLD; V C DIRAIMONDO; P H FORSHAM
Journal:  Metabolism       Date:  1960-01       Impact factor: 8.694

4.  Studies of the diurnal variation of plasma 17-hydroxycorticosteroids in man.

Authors:  G T PERKOFF; K EIK-NES; C A NUGENT; H L FRED; R A NIMER; L RUSH; L T SAMUELS; F H TYLER
Journal:  J Clin Endocrinol Metab       Date:  1959-04       Impact factor: 5.958

5.  A preliminary study of the use of 2-methyl-1, 2-bis (3-pyridyl)-1-propanone (SU 4885) as a test of pituitary function in man.

Authors:  G W BISSELL; A L SCOTT; W E FARNSWORTH; I WINKLER
Journal:  N Y State J Med       Date:  1959-10-01

6.  Pharmacology and biochemistry of some amphenone analogues and other adrenal cortical inhibitors.

Authors:  J J CHART; H SHEPPARD
Journal:  J Med Pharm Chem       Date:  1959-10

7.  The treatment of adrenal dysfunction.

Authors:  A GOLDFIEN; D H NELSON; G W THORN
Journal:  Med Clin North Am       Date:  1956-09       Impact factor: 5.456

8.  Clinical use of a new diagnostic agent, methopyrapone (SU-4885), in pituitary and adrenocortical disorders.

Authors:  E M GOLD; J R KENT; P H FORSHAM
Journal:  Ann Intern Med       Date:  1961-02       Impact factor: 25.391
  8 in total
  3 in total

1.  [Performance and interpretation of a shortened metyrapone test].

Authors:  H K Kley; H L Krüskemper
Journal:  Klin Wochenschr       Date:  1972-11-15

2.  Competitive protein-binding radioassays in the diagnosis of endocrine disorders.

Authors:  B E Murphy
Journal:  Can Med Assoc J       Date:  1972-02-19       Impact factor: 8.262

3.  [The diagnosis and differential diagnosis of Cushing's syndrome by means of an abbreviated dexamethasone test in the determination of corticosteroids in plasma].

Authors:  H Bethge; M T Brauns; H G Solbach; W Winkelmann; H Zimmermann
Journal:  Klin Wochenschr       Date:  1966-08-01
  3 in total

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