Literature DB >> 141280

Kinetic properties of the primary inhibitor of plasmin from human plasma.

U Christensen, I Clemmensen.   

Abstract

The interaction of human plasmin with the newly discovered alpha2-plasmin inhibitor was investigated. It was found from rate measurements that the reaction involves the rapid formation of a first enzyme-inhibitor complex, followed by the slow irreversible transition to another complex. L-Lysine influences the first step, but not the second.

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Year:  1977        PMID: 141280      PMCID: PMC1164709          DOI: 10.1042/bj1630389

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  9 in total

1.  Immunochemical distinction between antiplasmin and alpha-antitrypsin.

Authors:  D Collen; M Verstraete
Journal:  Thromb Res       Date:  1975-07       Impact factor: 3.944

Review 2.  ELEMENTARY STEPS IN ENZYME REACTIONS (AS STUDIED BY RELAXATION SPECTROMETRY).

Authors:  M EIGEN; G G HAMMES
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1963

3.  The primary inhibitor of plasmin in human plasma.

Authors:  S Müllertz; I Clemmensen
Journal:  Biochem J       Date:  1976-12-01       Impact factor: 3.857

4.  Kinetic studies of the urokinase catalysed conversion of NH2-terminal lysine plasminogen to plasmin.

Authors:  U Christensen; S Müllertz
Journal:  Biochim Biophys Acta       Date:  1977-01-11

5.  Comparison of the esterase activities of trypsin, plasmin, and thrombin on guanidinobenzoate esters. Titration of the enzymes.

Authors:  T Chase; E Shaw
Journal:  Biochemistry       Date:  1969-05       Impact factor: 3.162

6.  Different molecular forms of plasminogen and plasmin produced by urokinase in human plasma and their relation to protease inhibitors and lysis of fibrinogen and fibrin.

Authors:  S Müllertz
Journal:  Biochem J       Date:  1974-11       Impact factor: 3.857

7.  pH effects in plasmin-catalysed hydrolysis of alpha-N-benzoyl-L-arginine compounds.

Authors:  U Christensen
Journal:  Biochim Biophys Acta       Date:  1975-08-26

8.  Identification and some properties of a new fast-reacting plasmin inhibitor in human plasma.

Authors:  D Collen
Journal:  Eur J Biochem       Date:  1976-10-01

9.  Isolation and characterization of alpha2-plasmin inhibitor from human plasma. A novel proteinase inhibitor which inhibits activator-induced clot lysis.

Authors:  M Moroi; N Aoki
Journal:  J Biol Chem       Date:  1976-10-10       Impact factor: 5.157

  9 in total
  13 in total

1.  Purification and reaction mechanisms of the primary inhibitor of plasmin from human plasma.

Authors:  U Christensen; I Clemmensen
Journal:  Biochem J       Date:  1978-11-01       Impact factor: 3.857

2.  Stopped-flow fluorescence kinetics of bovine alpha 2-antiplasmin inhibition of bovine midiplasmin.

Authors:  S Christensen; L Sottrup-Jensen; U Christensen
Journal:  Biochem J       Date:  1995-01-01       Impact factor: 3.857

3.  Alpha2-plasmin inhibitor and alpha2-macroglobulin-plasmin complexes in plasma. Quantitation by an enzyme-linked differential antibody immunosorbent assay.

Authors:  P C Harpel
Journal:  J Clin Invest       Date:  1981-07       Impact factor: 14.808

4.  Different N-terminal forms of alpha 2-plasmin inhibitor in human plasma.

Authors:  K Bangert; A H Johnsen; U Christensen; S Thorsen
Journal:  Biochem J       Date:  1993-04-15       Impact factor: 3.857

Review 5.  Natural inhibitors of fibrinolysis.

Authors:  D Collen
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1980

6.  The human alpha(2)-plasmin inhibitor: functional characterization of the unique plasmin(ogen)-binding region.

Authors:  Simon S Gerber; Sofia Lejon; Michael Locher; Johann Schaller
Journal:  Cell Mol Life Sci       Date:  2010-01-29       Impact factor: 9.261

Review 7.  The plasmin-antiplasmin system: structural and functional aspects.

Authors:  Johann Schaller; Simon S Gerber
Journal:  Cell Mol Life Sci       Date:  2010-12-07       Impact factor: 9.261

8.  Alpha 2-antiplasmin supplementation inhibits tissue plasminogen activator-induced fibrinogenolysis and bleeding with little effect on thrombolysis.

Authors:  J I Weitz; B Leslie; J Hirsh; P Klement
Journal:  J Clin Invest       Date:  1993-04       Impact factor: 14.808

9.  The AH-site of plasminogen and two C-terminal fragments. A weak lysine-binding site preferring ligands not carrying a free carboxylate function.

Authors:  U Christensen
Journal:  Biochem J       Date:  1984-10-15       Impact factor: 3.857

10.  Kinetics of plasmin inhibition in the presence of a synthetic tripeptide substrate. The reaction with pancreatic trypsin inhibitor and two forms of alpha 2-plasmin inhibitor.

Authors:  L C Petersen; I Clemmensen
Journal:  Biochem J       Date:  1981-10-01       Impact factor: 3.857

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