| Literature DB >> 14122440 |
R N RAY, J B CHATTERJEA, R N CHAUDHURI.
Abstract
Subjects with sickle cell trait have been known to offer resistance to induced Plasmodium falciparum infection. The resistance to malarial infection in other haemoglobinopathic disorders is not clearly known. Investigations were undertaken to test for resistance to malaria in Hb E thalassaemia disease. Compared to controls, subjects with Hb E thalassaemia disease were found to have significant resistance to induced Plasmodium vivax infection.Entities:
Keywords: ANEMIA, SICKLE CELL; CLINICAL RESEARCH; ERYTHROCYTES; FETAL HEMOGLOBIN; GLUCOSEPHOSPHATE DEHY- DROGENASE DEFICIENCY; GLUTATHIONE; HEMOGLOBINS, ABNORMAL; INDIA; MALARIA; NEGROES; PLASMODIUM VIVAX; THALASSEMIA; UNITED STATES
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Year: 1964 PMID: 14122440 PMCID: PMC2554904
Source DB: PubMed Journal: Bull World Health Organ ISSN: 0042-9686 Impact factor: 9.408