| Literature DB >> 141132 |
B G Solheim, A Flatmark, E Enger, J Jervell, E Thorsby.
Abstract
The influence of HLA matching has been studied in the Norwegian material of 142 living related and 311 cadaveric transplants. Graft survival corresponded closely to the degree of HLA haplotype disparity between donors and recipients. Furthermore, graft survival was less in combinations being incompatible for the serologically defined HLA-A and -B antigens as compared to compatible combinations. A weak MLC response, indicating a possible sharing of the HLA-D determinants between donor and recipient, was also associated with superior graft survival, even in the presence of HLA-A and -B disparity. Matching for HLA-C in addition to HLA-A and -B did not seem to improve graft survival.Entities:
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Year: 1977 PMID： 141132
Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066