Literature DB >> 14112273

STUDIES ON ARTIFICIAL ANTIGENS. II. THE ANTIGENICITY IN GUINEA PIGS OF ARSANILIC ACID CONJUGATES OF COPOLYMERS OF D- OR L-ALPHA-AMINO ACIDS.

B BENACERRAF, A OJEDA, P H MAURER.   

Abstract

An effort was made to immunize guinea pigs with arsanilic acid conjugates of copolymers of D- and L-alpha-amino acids; ASD-GAT and ASL-GAT. An immune response was observed only in the case of ASL-GAT. Antibodies specific for the arsanilic acid hapten were produced which could also react with ASD-GAT or ASGPA. These findings indicate that the proper metabolism of the antigen may be essential to the induction of the immune response.

Entities:  

Keywords:  ALANINE; ANTIGEN-ANTIBODY REACTIONS; ANTIGENS; ARSENICALS; EXPERIMENTAL LAB STUDY; GLUTAMATES; GUINEA PIGS; LYSINE; PRECIPITIN TESTS; PROTEIN METABOLISM; TYROSINE

Mesh：

Substances：

Year:  1963        PMID： 14112273      PMCID： PMC2137701          DOI： 10.1084/jem.118.6.945

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  14 in total

1.  ANTIGENICITY OF POLYPEPTIDES (POLY-ALPHA-AMINO ACIDS). VIII. STUDIES IN GUINEA PIGS.

Authors:  P H MAURER; T CASHMAN
Journal:  J Immunol       Date:  1963-03       Impact factor: 5.422

2.  Role of optical isomers in determining the antigenicity of synthetic polypeptides.

Authors:  T J GILL; H J GOULD; P DOTY
Journal:  Nature       Date:  1963-02-23       Impact factor: 49.962

3.  Macrophages, nucleic acids, and the induction of antibody formation. A review.

Authors:  M B RITTENBERG; E L NELSON
Journal:  Am Nat       Date:  1960 Sep-Oct       Impact factor: 3.926

4.  Synthesis and chemical properties of poly-alpha-amino acids.

Authors:  E KATCHALSKI; M SELA
Journal:  Adv Protein Chem       Date:  1958

5.  Immediate reactions in the skin of experimental animals provoked by antibody-antigen interaction.

Authors:  Z OVARY
Journal:  Prog Allergy       Date:  1958

6.  Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemagglutination and hemagglutination-inhibition reactions with tannic acid and protein-treated red blood cells.

Authors:  A B STAVITSKY
Journal:  J Immunol       Date:  1954-05       Impact factor: 5.422

7.  SEROLOGICAL REACTIONS WITH SIMPLE CHEMICAL COMPOUNDS (PRECIPITIN REACTIONS).

Authors:  K Landsteiner; J van der Scheer
Journal:  J Exp Med       Date:  1932-08-31       Impact factor: 14.307

8.  Antigenicity of polypeptides (poly alpha amino acids). VII. Studies in humans.

Authors:  P H MAURER; B F GERULAT; P PINCHUCK
Journal:  J Exp Med       Date:  1962-10-01       Impact factor: 14.307

9.  Immunological specificity of delayed and immediate hypersensitivity reactions.

Authors:  B BENACERRAF; B B LEVINE
Journal:  J Exp Med       Date:  1962-05-01       Impact factor: 14.307

10.  Properties of guinea pig 7S antibodies. III. Identification of antibodies involved in complement fixation and hemolysis.

Authors:  K J BLOCH; F M KOURILSKY; Z OVARY; B BENACERRAF
Journal:  J Exp Med       Date:  1963-06-01       Impact factor: 14.307
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  18 in total

1.  Mechanisms of genetic control of immune responses. II. Nonresponsiveness in BALB/c GT-specific cell-mediated immune responses does not correlate with the absence of functional T cells or the induction of suppressor T cells.

Authors:  M K Kennedy; M K Jenkins; S D Miller
Journal:  Immunogenetics       Date:  1986       Impact factor: 2.846

Review 2.  Comparison of the haemoglobin and gamma globulin molecule from the aspect of structure and the genetic control of synthesis.

Authors:  B Skárová
Journal:  Folia Microbiol (Praha)       Date:  1967       Impact factor: 2.099

3.  Differences in the immune response of rabbits to p-aminobenzoic acid and sulphanilic acid, conjugated with BGG.

Authors:  B Skárová; I Ríha; V Pesák
Journal:  Folia Microbiol (Praha)       Date:  1968       Impact factor: 2.099

4.  Anaphylactic antibodies in mice genetically selected for antibody production.

Authors:  A Prouvost-Danon; C Stiffel; D Mouton; G Biozzi
Journal:  Immunology       Date:  1971-01       Impact factor: 7.397

5.  Genetic control of the immune response. I. Differences in immune response of inbred strains of mice to p-aminobenzoic acid and sulphanilic acid.

Authors:  B Skárová; I Ríha
Journal:  Folia Microbiol (Praha)       Date:  1969       Impact factor: 2.099

6.  Relation between optical configuration and immunogenicity of synthetic polypeptides.

Authors:  F Borek; Y Stupp; S Fuchs; M Sela
Journal:  Biochem J       Date:  1965-09       Impact factor: 3.857

7.  Genetically controlled specific immunological unresponsiveness.

Authors:  W R Sobey; J M Magrath; A H Reisner
Journal:  Immunology       Date:  1966-11       Impact factor: 7.397

8.  IN VITRO STUDIES OF CELLULAR HYPERSENSITIVITY. II. RELATIONSHIP OF DELAYED HYPERSENSITIVITY AND INHIBITION OF CELL MIGRATION BY PICRYLATED PROTEINS.

Authors:  R R CARPENTER; M W BRANDRISS
Journal:  J Exp Med       Date:  1964-12-01       Impact factor: 14.307

9.  Adjuvant activities of chemically modified water-soluble substances from Mycobacterium tuberculosis.

Authors:  D Migliore-Samour; F Floc'h; R Maral; G H Werner; P Jollès
Journal:  Immunology       Date:  1977-10       Impact factor: 7.397

10.  Antigenicity of polypeptides (poly alpha amino acids). XVI. Genetic control of immunogenicity of synthetic polypeptides in mice.

Authors:  P Pinchuck; P H Maurer
Journal:  J Exp Med       Date:  1965-10-01       Impact factor: 14.307
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