| Literature DB >> 14110749 |
Abstract
gamma-Globulin fractions isolated from guinea-pig serum by chromatography on diethylaminoethyl cellulose exhibited all the properties of kallikrein. From a range of amino acid esters tested, only esters of arginine and lysine were hydrolysed; the esterase and capillary permeability-increasing activities of different samples were correlated. Both esterase and permeability-increasing activities could be increased by the addition of certain albumin-rich fractions or of glass beads previously treated with guinea-pig serum.Entities:
Keywords: ARGININE; CAPILLARY PERMEABILITY; CHROMATOGRAPHY; ESTERASES; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; GUINEA PIGS; KALLIKREIN; LYSINE; METABOLISM; PERMEABILITY GLOBULINS
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Year: 1963 PMID: 14110749 PMCID: PMC1703887 DOI: 10.1111/j.1476-5381.1963.tb02017.x
Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN: 0366-0826