Literature DB >> 14107465

INSECT CHEMOSTERILANTS WITH LOW TOXICITY FOR MAMMALS.

S C CHANG, P H TERRY, A B BORKOVEC.   

Abstract

Hexamethylphosphoramide and hexamethylmelamine are effective as male house fly chemosterilants. Both compounds are structurally similar to the two highly active sterilants tepa and tretamine, but they differ from the aziridinyl compounds in their low toxicity for mammals and in their lack of alkylating properties. This discovery of nonalkylating male sterilants of low toxicity should substantially increase the scope and practicality of the sterilemale control method.

Entities:  

Keywords:  AMIDES; CHEMISTRY; HOUSEFLIES; INSECTICIDES; METHONIUM COMPOUNDS; PHOSPHORUS; STERILIZATION, SEXUAL; TOXICOLOGIC REPORT

Mesh:

Substances:

Year:  1964        PMID: 14107465     DOI: 10.1126/science.144.3614.57

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  8 in total

1.  The chronic toxicity of hexamethylphosphoramide in rats.

Authors:  R D Kimbrough; T B Gaines
Journal:  Bull Environ Contam Toxicol       Date:  1973-10       Impact factor: 2.151

2.  Comparative effects of tretamine, tepa, apholate and their structural analogs on human chromsomes in vitro.

Authors:  T H Chang; W Klassen
Journal:  Chromosoma       Date:  1968       Impact factor: 4.316

3.  The metabolism of hexamethylphosphoramide and hexamethylthiophosphoramide.

Authors:  A R Jones; J S Bertram
Journal:  Experientia       Date:  1968-04-15

4.  Chemosterilants for Control of Insects and Insect Vectors of Disease.

Authors:  Richard H G Baxter
Journal:  Chimia (Aarau)       Date:  2016-10       Impact factor: 1.509

5.  Enhancement of natural and experimental respiratory mycoplasmosis in rats by hexamethylphosphoramide.

Authors:  R G Overcash; J R Lindsey; G H Cassel; H J Baker
Journal:  Am J Pathol       Date:  1976-01       Impact factor: 4.307

6.  The cross-linking agent hexamethylphosphoramide predominantly induces intra-locus and multi-locus deletions in postmeiotic germ cells of Drosophila.

Authors:  I Aguirrezabalaga; M J Nivard; M A Comendador; E W Vogel
Journal:  Genetics       Date:  1995-02       Impact factor: 4.562

7.  Metaplastic changes of nasal respiratory epithelium in rats exposed to hexamethylphosphoramide (HMPA) by inhalation.

Authors:  K P Lee; H J Trochimowicz
Journal:  Am J Pathol       Date:  1982-01       Impact factor: 4.307

8.  Chemosterilization of Culex pipiens fatigans Wiedemann by exposure of aquatic stages. 2. Sterilization potential of certain phosphoramides and s-triazines.

Authors:  K K Grover; M K Pillai
Journal:  Bull World Health Organ       Date:  1969       Impact factor: 9.408

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.