Literature DB >> 14107432

CEREBELLAR ATAXIA IN HAMSTERS INOCULATED WITH RAT VIRUS.

L KILHAM, G MARGOLIS.   

Abstract

Chronic ataxia associated with hypoplasia of the cerebellum was induced by intracerebral inoculation of newborn hamsters with various strains of rat virus. The condition usually became recognizable within 3 weeks of inoculation and remained static as the animals matured. Preliminary studies suggest that hypoplasia is induced by the rat virus acting on the outer germinal layer of the cerebellum at a critical time in its ontogenic development.

Entities:  

Keywords:  ANIMALS, NEWBORN; ATAXIA; CEREBELLAR DISEASES; EXPERIMENTAL LAB STUDY; HAMSTERS; PATHOLOGY; VERTEBRATE VIRUSES

Mesh:

Year:  1964        PMID: 14107432     DOI: 10.1126/science.143.3610.1047

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


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5.  Viral etiology of spontaneous ataxia of cats.

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7.  Inhibition of mitosis and macromolecular synthesis in rat embryo cells by Kilham rat virus.

Authors:  R W Tennant
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8.  Spontaneous hepatitis and cerebellar "hypoplasia" in suckling rats due to congenital infections with rat virus.

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  8 in total

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