Literature DB >> 1409198

Portal vein thrombosis in a complicated case of Crohn's disease.

A Crowe1, N Taffinder, G T Layer, A Irvine, R J Nicholls.   

Abstract

Portal vein thrombosis is a rare complication of ulcerative colitis and is invariably fatal. This report describes a patient with severe Crohn's disease who underwent elective surgery complicated by an anastomotic disruption with faecal peritonitis. Following emergency laparotomy he developed left hypochondrial pain which was a manifestation of splenomegaly consequent upon portal vein thrombosis. Anticoagulation was successful in preventing further spread of the thrombosis as monitored by colour Doppler ultrasound. Severe active disease, surgery and sepsis have been recognized as predisposing factors for thromboembolic complications in inflammatory bowel disease and this patient was exposed to all three. It is conceivable that portal vein thromboses occur more commonly than suspected and ultrasound scanning could ascertain the prevalence if performed prospectively.

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Year:  1992        PMID: 1409198      PMCID: PMC2399275          DOI: 10.1136/pgmj.68.798.291

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  12 in total

1.  Portal vein thrombosis in myeloproliferative disease. Uses of thrombolytic and antiplatelet treatment.

Authors:  H Fidler; A Booth; H J Hodgson; J Calam; L Luzatto; J M Hughes
Journal:  BMJ       Date:  1990-03-03

2.  Hepatic and portal vein-thrombosis.

Authors:  B J Boughton
Journal:  BMJ       Date:  1991-01-26

Review 3.  Procoagulant activity in gastroenterology.

Authors:  A Wakefield; Z Cohen; G Levy
Journal:  Gut       Date:  1990-02       Impact factor: 23.059

4.  Pathogenesis of Crohn's disease: multifocal gastrointestinal infarction.

Authors:  A J Wakefield; A M Sawyerr; A P Dhillon; R M Pittilo; P M Rowles; A A Lewis; R E Pounder
Journal:  Lancet       Date:  1989-11-04       Impact factor: 79.321

5.  Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine.

Authors:  T T MacDonald; P Hutchings; M Y Choy; S Murch; A Cooke
Journal:  Clin Exp Immunol       Date:  1990-08       Impact factor: 4.330

6.  Vascular complications of inflammatory bowel disease.

Authors:  R W Talbot; J Heppell; R R Dozois; R W Beart
Journal:  Mayo Clin Proc       Date:  1986-02       Impact factor: 7.616

7.  Portal vein thrombosis in ulcerative colitis.

Authors:  A R Aronson; F U Steinheber
Journal:  N Y State J Med       Date:  1971-10

8.  Arterial thrombosis in Crohn's disease.

Authors:  C E Halliday; M J Farthing
Journal:  Med J Aust       Date:  1988-11-21       Impact factor: 7.738

9.  No evidence for a prethrombotic state in stable chronic inflammatory bowel disease.

Authors:  E Knot; J W Ten Cate; O C Leeksma; G N Tytgat; J Vreeken
Journal:  J Clin Pathol       Date:  1983-12       Impact factor: 3.411

10.  Modulation of endothelial cell hemostatic properties by tumor necrosis factor.

Authors:  P P Nawroth; D M Stern
Journal:  J Exp Med       Date:  1986-03-01       Impact factor: 14.307

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  4 in total

Review 1.  Management of acute non-cirrhotic and non-malignant portal vein thrombosis: a systematic review.

Authors:  T C Hall; G Garcea; M Metcalfe; D Bilku; A R Dennison
Journal:  World J Surg       Date:  2011-11       Impact factor: 3.352

2.  Postoperative portal and splenic vein thrombosis in children: identification of risk factors.

Authors:  Tadao Okada; Fumiaki Sasaki; Nozomi Minagawa; Satsuki Naito; Ryouji Kobayashi; Mitsuru Kubota; Satoru Todo
Journal:  Pediatr Surg Int       Date:  2005-11       Impact factor: 1.827

Review 3.  Portal venous gas and thrombosis in a Chinese patient with fulminant Crohn's colitis: a case report with literature review.

Authors:  Simon Siu-Man Ng; Raymond Ying-Chang Yiu; Janet Fung-Yee Lee; Jimmy Chak-Man Li; Ka-Lau Leung
Journal:  World J Gastroenterol       Date:  2006-09-14       Impact factor: 5.742

4.  Effects of low molecular weight heparin on platelet surface P-selectin expression and serum interleukin-8 production in rats with trinitrobenzene sulphonic acid-induced colitis.

Authors:  Bing Xia; Hong Han; Ke-Jian Zhang; Jin Li; Guang-Song Guo; Ling-Ling Gong; Xian-Chang Zeng; Jun-Yan Liu
Journal:  World J Gastroenterol       Date:  2004-03-01       Impact factor: 5.742

  4 in total

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