| Literature DB >> 14088077 |
N WALD, A C UPTON, V K JENKINS, W H BORGES.
Abstract
Granulocytic leukemia, induced in the primary mouse by x-irradiation, was serially transmitted to RF/Up mice. An extra chromosome, as well as a morphologicaly unusual chromosome, was found in the bone marrow cells of all the leukemic mice that had been injected previously either with leukemic spleen cells or with cell-free ultracentrifugates. This suggests that the changes in the chromosomes are caused by a virus.Entities:
Keywords: CHROMOSOME ABNORMALITIES; EXPERIMENTAL LAB STUDY; LEUKEMIA, RADIATION-INDUCED; MICE
Mesh：
Year: 1964 PMID： 14088077 DOI： 10.1126/science.143.3608.810
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728