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Literature DB >> 14087623

LOCALIZATION OF ANTIBODIES IN GROUP I AND GROUP II GAMMA-GLOBULINS.

Abstract

A wide assortment of antibodies has been analysed by qualitative and quantitative techniques for their content of group I- and group II-type gamma-globulin molecules. These included Rh antibodies, isoagglutinins, thyroglobulin antibodies, dextran antibodies, and teichoic acid antibodies. All the antibodies studied showed the presence of both groups. However, the ratio of the two varied widely in different individuals and diverged markedly from the ratio in the total gamma-globulin of the individual. Two antibodies isolated from the serum of the same individual showed different ratios for the two groups.

Entities: Chemical

Keywords: ANTIGEN-ANTIBODY REACTIONS; BENCE JONES PROTEIN; DEXTRAN; ELECTROPHORESIS; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; PHOSPHATES; RABBITS; RH FACTORS; THYROGLOBULIN

Mesh：

Substances：

Year: 1963 PMID： 14087623 PMCID： PMC2137674 DOI： 10.1084/jem.118.5.817

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

7 in total

1. On structural and functional relations between antibodies and proteins of the gamma-system.

Authors: G M EDELMAN; B BENACERRAF
Journal: Proc Natl Acad Sci U S A Date: 1962-06-15 Impact factor: 11.205

2. TWO TYPES OF gamma-MYELOMA PROTEINS, beta(2A)-MYELOMA PROTEINS, gamma(1)-MACROGLOBULINS, AND BENCE JONES PROTEINS IDENTIFIED BY TWO GROUPS OF COMMON ANTIGENIC DETERMINANTS.

Authors: J L Fahey; A Solomon
Journal: J Clin Invest Date: 1963-06 Impact factor: 14.808

3. Individual Antigenic Specificity of Isolated Antibodies.

Authors: H G Kunkel; M Mannik; R C Williams
Journal: Science Date: 1963-06-14 Impact factor: 47.728

4. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

5. TWO MAJOR TYPES OF NORMAL 7S gamma-GLOBULIN.

Authors: M Mannik; H G Kunkel
Journal: J Exp Med Date: 1963-01-31 Impact factor: 14.307

6. CLASSIFICATION OF MYELOMA PROTEINS, BENCE JONES PROTEINS, AND MACROGLOBULINS INTO TWO GROUPS ON THE BASIS OF COMMON ANTIGENIC CHARACTERS.

Authors: M Mannik; H G Kunkel
Journal: J Exp Med Date: 1962-11-30 Impact factor: 14.307

7. Antigenic relationships of Bence Jones proteins, myeloma globulins, and normal human gama-globulin.

Authors: S MIGITA; F W PUTNAM
Journal: J Exp Med Date: 1963-01-01 Impact factor: 14.307

7 in total

19 in total

1. Cerebrospinal fluid and serum light polypeptide chains in 160 patients with various nervous system disorders.

Authors: O Kolar; E Anthony
Journal: Z Neurol Date: 1971

2. Light chain types in plasma cells that produce IgD.

Authors: B Pernis; M Governa; D S Rowe
Journal: Immunology Date: 1969-05 Impact factor: 7.397

3. Monoclonal immunoglobulins in congenital toxoplasmosis.

Authors: V A Oxelius
Journal: Clin Exp Immunol Date: 1972-07 Impact factor: 4.330

4. Electrophoretic distribution of kappa and lambda immunoglobulin light chain determinants in serum and cerebrospinal fluid in multiple sclerosis.

Authors: O Zettervall; H Link
Journal: Clin Exp Immunol Date: 1970-09 Impact factor: 4.330

5. Kappa:lambda light chain ratio in IgG eluted from rheumatoid arthritis synovium.

Authors: F D Lindström
Journal: Clin Exp Immunol Date: 1970-07 Impact factor: 4.330

6. Multiple sclerosis: disturbed kappa: lambda chain ratio of immunoglobulin G in cerebrospinal fluid.

Authors: H Link; O Zettervall
Journal: Clin Exp Immunol Date: 1970-03 Impact factor: 4.330

7. The immunologic character of acquired inhibitors of antihemophilic globulin (factor 8) and the kinetics of their interaction with factor 8.

Authors: S S Shapiro
Journal: J Clin Invest Date: 1967-02 Impact factor: 14.808