Literature DB >> 14086088

MECHANISM OF ACTION OF STAPHYLOCCAL ALPHA-HEMOLYSIN. II. ANALYSIS OF THE KINETIC CURVE AND INHIBITION BY SPECIFIC ANTIBODY.

A MAARUCCI.   

Abstract

Marucci, Americo A. (Upstate Medical Center, Syracuse, N.Y.). Mechanism of action of staphylococcal alpha-hemolysin. II. Analysis of the kinetic curve and inhibition by specific antibody. J. Bacteriol. 86:1189-1195. 1963.-At least two steps are necessary before the rabbit erythrocyte is lysed by staphylococcal alpha-hemolysin. The first step involves the reaction of alpha-hemolysin with the red cell. The second step, leading to the release of hemoglobin, is an intrinsic reaction of the damaged red cell and takes place without further participation of hemolysin. The speed of this intrinsic reaction is temperature-dependent. Erythrocytes taken from the same rabbit do not vary in their susceptibility to the alpha-hemolysin. From the results of the experiments described herein, a preliminary hypothesis on the mechanism of action of staphylococcal alpha-hemolysin is given.

Entities:  

Keywords:  ANTIBODIES; ERYTHROCYTES; EXPERIMENTAL LAB STUDY; HEMOGLOBIN; HEMOLYSINS; RABBITS; STAPHYLOCOCCUS; TEMPERATURE

Mesh：

Substances：

Year:  1963        PMID： 14086088      PMCID： PMC283628     

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  6 in total

1.  MECHANISM OF ACTION OF STAPHYLOCOCCAL ALPHA-HEMOLYSIN. I. SOME FACTORS INFLUENCING THE MEASUREMENT OF ALPHA-HEMOLYSIN.

Authors:  A A MARUCCI
Journal:  J Bacteriol       Date:  1963-12       Impact factor: 3.490

2.  Antibody to enzymes--a three-component system. Introduction: immunochemistry of enzymes.

Authors:  B CINADER
Journal:  Ann N Y Acad Sci       Date:  1963-05-08       Impact factor: 5.691

3.  Isolation and composition of staphylococcal alpha toxin.

Authors:  A W BERNHEIMER; L L SCHWARTZ
Journal:  J Gen Microbiol       Date:  1963-03

4.  Studies with staphylococcal toxins. V. Possible identification of alpha hemolysin with a proteolytic enzyme.

Authors:  J ROBINSON; F S THATCHER; J MONTFORD
Journal:  Can J Microbiol       Date:  1960-04       Impact factor: 2.419

5.  Some characteristics of Staphylococcus alpha haemolysin.

Authors:  I LOMINSKI; J P ARBUTHNOTT
Journal:  J Pathol Bacteriol       Date:  1962-04

6.  The characterization of staphylococcal toxins. I. The electrophoretic migration of the alpha hemolytic, dermonecrotic, lethal, and leucocidal activities of crude toxin.

Authors:  S KUMAR; R K LINDORFER
Journal:  J Exp Med       Date:  1962-06-01       Impact factor: 14.307
  6 in total
  7 in total

Review 1.  The hemolysins of Staphylococcus aureus.

Authors:  G M Wiseman
Journal:  Bacteriol Rev       Date:  1975-12

2.  MECHANISM OF ACTION OF STAPHYLOCOCCAL ALPHA-HEMOLYSIN. I. SOME FACTORS INFLUENCING THE MEASUREMENT OF ALPHA-HEMOLYSIN.

Authors:  A A MARUCCI
Journal:  J Bacteriol       Date:  1963-12       Impact factor: 3.490

3.  Comparison of purified alpha-toxins from various strains of Staphylococcus aureus.

Authors:  R L Goode; J N Baldwin
Journal:  Appl Microbiol       Date:  1974-07

4.  Inhibition of staphylococcal alpha-toxin. A kinetic evaluation of aromatic polysulphonic acids as inhibitors of haemolysis.

Authors:  M R Wright; J P Arbuthnott; I R Lominski
Journal:  Biochem J       Date:  1968-06       Impact factor: 3.857

5.  [Demonstration of antistaphylococcal-alpha-hemolysin by means of stable antigen].

Authors:  F Harter; H G Schwick; K Störiko
Journal:  Klin Wochenschr       Date:  1965-10-15

6.  Properties of the Hemolytic Activities of Escherichia coli.

Authors:  E C Short; H J Kurtz
Journal:  Infect Immun       Date:  1971-05       Impact factor: 3.441

7.  Bacteriocin (hemolysin) of Streptococcus zymogenes.

Authors:  S F Basinger; R W Jackson
Journal:  J Bacteriol       Date:  1968-12       Impact factor: 3.490
  7 in total

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