| Literature DB >> 14084752 |
Abstract
Chagas disease due to a trypanosome infection may lead to extensive destruction of ganglion cells in the peripheral autonomic system and may result in gross enlargement of the oesophagus, colon, and heart. From studies on nerve cell counts it is concluded that the number of ganglion cells in the oesophagus must be reduced to less than half to produce functional disturbances in the oesophagus and to one tenth to produce a megaoesophagus. Problems of terminology are discussed.Entities:
Keywords: BRAZIL; BRONCHIECTASIS; ESOPHAGUS; GANGLIA, AUTONOMIC; HEART ENLARGEMENT; MEGACOLON; STOMACH DILATATION; TRYPANOSOMIASIS, SOUTH AMERICAN
Mesh:
Year: 1963 PMID: 14084752 PMCID: PMC1413478 DOI: 10.1136/gut.4.4.399
Source DB: PubMed Journal: Gut ISSN: 0017-5749 Impact factor: 23.059