Literature DB >> 14080318

CYSTINURIA: IN VITRO DEMONSTRATION OF AN INTESTINAL TRANSPORT DEFECT.

S THIER, M FOX, S SEGAL, L E ROSENBERG.   

Abstract

A defect in the transport of L-cystine and L-lysine has been found in the intestinal mucosa of patients with cystinuria. Transport studies in normal intestinal mucosa, in contrast to similar studies in the kidney, show that cystine and lysine are mutually inhibitory.

Entities:  

Keywords:  ARGININE; CYSTINE; CYSTINURIA; EXPERIMENTAL LAB STUDY; GLYCINE; JEJUNUM; PROTEIN METABOLISM

Mesh：

Substances：

Year:  1964        PMID： 14080318     DOI： 10.1126/science.143.3605.482

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  17 in total

1.  DEFECTIVE UPTAKE OF BASIC AMINO ACIDS AND L-CYSTINE BY INTESTINAL MUCOSA OF PATIENTS WITH CYSTINURIA.

Authors:  C F MCCARTHY; J L BORLAND; H J LYNCH; E E OWEN; M P TYOR
Journal:  J Clin Invest       Date:  1964-08       Impact factor: 14.808

2.  CYSTINURIA: DEFECTIVE INTESTINAL TRANSPORT OF DIBASIC AMINO ACIDS AND CYSTINE.

Authors:  S O THIER; S SEGAL; M FOX; A BLAIR; L E ROSENBERG
Journal:  J Clin Invest       Date:  1965-03       Impact factor: 14.808

3.  TRANSPORT OF NEUTRAL AND DIBASIC AMINO ACIDS BY HUMAN LEUKOCYTES: ABSENCE OF DEFECT IN CYSTINURIA.

Authors:  L E ROSENBERG; S DOWNING
Journal:  J Clin Invest       Date:  1965-08       Impact factor: 14.808

Review 4.  Cystine growth inhibition through molecular mimicry: a new paradigm for the prevention of crystal diseases.

Authors:  Michael H Lee; Amrik Sahota; Michael D Ward; David S Goldfarb
Journal:  Curr Rheumatol Rep       Date:  2015-05       Impact factor: 4.592

5.  The molecular basis of cystinuria: the role of the rBAT gene.

Authors:  M Palacín; C Mora; J Chillarón; M J Calonge; R Estévez; D Torrents; X Testar; A Zorzano; V Nunes; J Purroy; X Estivill; P Gasparini; L Bisceglia; L Zelante
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

6.  Evidence suggesting that the minimal functional unit of a renal cystine transporter is a heterodimer and its implications in cystinuria.

Authors:  S S Tate
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

Review 7.  [Absorption and malabsorption of protein digestion products].

Authors:  D M Matthews
Journal:  Klin Wochenschr       Date:  1969-04-15

8.  Amino acid patterns in cystinuric families.

Authors:  S Kelly; W Copeland
Journal:  J Med Genet       Date:  1968-12       Impact factor: 6.318

Review 9.  Hyperaminoaciduria in childhood.

Authors:  V N Ingle
Journal:  Indian J Pediatr       Date:  1966-02       Impact factor: 1.967

10.  Transport of dibasic amino acids, cystine, and tryptophan by cultured human fibroblasts: absence of a defect in cystinuria and Hartnup disease.

Authors:  U Groth; L E Rosenberg
Journal:  J Clin Invest       Date:  1972-08       Impact factor: 14.808
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