Literature DB >> 1407958

Retino-choroidal changes in endotoxin-induced uveitis in the rat.

J M Ruiz-Moreno1, B Thillaye, Y de Kozak.   

Abstract

A single injection of 100 micrograms of lipopolysaccharide from Salmonella typhimurium in the foot pads of Lewis rats induced acute inflammation of the eye. Clinically, the disease started as early as 0.5 h and peaked 18 h after the inoculation. The aqueous protein concentration was increased after the inoculation. Histopathologically, cellular infiltrates and proteinaceous exudates were observed in the anterior segment (anterior chamber, iris and ciliary body). In addition to those changes described in previous reports, the examination of the posterior segment showed retinal vasculitis, hemorrhagic exudates, focal destruction of photoreceptor cells and choroidal infiltration.

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Year:  1992        PMID： 1407958     DOI： 10.1159/000267163

Source DB:  PubMed          Journal:  Ophthalmic Res        ISSN： 0030-3747            Impact factor:   2.892


  18 in total

1.  Macrophages and MHC class II positive cells in the choroid during endotoxin induced uveitis.

Authors:  P Yang; A F de Vos; A Kijlstra
Journal:  Br J Ophthalmol       Date:  1997-05       Impact factor: 4.638

2.  Suppressive effects of selectin inhibitor SKK-60060 on the leucocyte infiltration during endotoxin induced uveitis.

Authors:  K Yamashiro; J Kiryu; A Tsujikawa; A Nonaka; K Nishijima; H Kamizuru; K Miyamoto; Y Honda; T Jomori; Y Ogura
Journal:  Br J Ophthalmol       Date:  2003-04       Impact factor: 4.638

Review 3.  A potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseases.

Authors:  Saumya Pandey; Satish K Srivastava; Kota V Ramana
Journal:  Expert Opin Investig Drugs       Date:  2012-01-28       Impact factor: 6.206

4.  Experimental melanin-induced uveitis in the Fischer 344 rat is inhibited by anti-CD4 monoclonal antibody, but not by mannose-6-phosphate.

Authors:  J R Smith; P H Hart; C R Parish; S D Standfield; D J Coster; K A Williams
Journal:  Clin Exp Immunol       Date:  1999-01       Impact factor: 4.330

5.  T-bet expression in the iris and spleen parallels disease expression during endotoxin-induced uveitis.

Authors:  Bing Li; Peizeng Yang; Liqun Chu; Hongyan Zhou; Xiangkun Huang; Lianxiang Zhu; Aize Kijlstra
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2006-08-04       Impact factor: 3.117

6.  Arginase activity mediates retinal inflammation in endotoxin-induced uveitis.

Authors:  Wenbo Zhang; Babak Baban; Modesto Rojas; Sohrab Tofigh; Suvika K Virmani; Chintan Patel; M Ali Behzadian; Maritza J Romero; Robert W Caldwell; Ruth B Caldwell
Journal:  Am J Pathol       Date:  2009-07-09       Impact factor: 4.307

7.  Differential expression of Kir4.1 and aquaporin 4 in the retina from endotoxin-induced uveitis rat.

Authors:  Xiao-Qiang Liu; Hideyuki Kobayashi; Zi-Bing Jin; Akihiko Wada; Nobuhis Nao-I
Journal:  Mol Vis       Date:  2007-03-01       Impact factor: 2.367

8.  Protein kinase Czeta (PKCzeta) regulates ocular inflammation and apoptosis in endotoxin-induced uveitis (EIU): signaling molecules involved in EIU resolution by PKCzeta inhibitor and interleukin-13.

Authors:  Yvonne de Kozak; Boubaker Omri; Justine R Smith; Marie-Christine Naud; Brigitte Thillaye-Goldenberg; Patricia Crisanti
Journal:  Am J Pathol       Date:  2007-04       Impact factor: 4.307

Review 9.  Role of the retinal vascular endothelial cell in ocular disease.

Authors:  Arpita S Bharadwaj; Binoy Appukuttan; Phillip A Wilmarth; Yuzhen Pan; Andrew J Stempel; Timothy J Chipps; Eric E Benedetti; David O Zamora; Dongseok Choi; Larry L David; Justine R Smith
Journal:  Prog Retin Eye Res       Date:  2012-09-11       Impact factor: 21.198

10.  Mast cells modulate the inflammatory process in endotoxin-induced uveitis.

Authors:  Pierre Sebastião da Silva; Ana Paula Girol; Sonia M Oliani
Journal:  Mol Vis       Date:  2011-05-08       Impact factor: 2.367
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