Literature DB >> 14077537

POISONING BY DDT: RELATION BETWEEN CLINICAL SIGNS AND CONCENTRATION IN RAT BRAIN.

W E DALE, T B GAINES, W J HAYES, G W PEARCE.   

Abstract

The severity of signs of poisoning in rats after a single dose of DDT is directly proportional to the concentration of the compound in their brains. The concentrations associated with death after one large dose are about the same as those after many smaller doses.

Entities:  

Keywords:  BRAIN; DDT; HISTOCYTOCHEMISTRY; RATS; TOXICOLOGIC REPORT

Mesh:

Substances:

Year:  1963        PMID: 14077537     DOI: 10.1126/science.142.3598.1474

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  13 in total

1.  [ON THE DISTRIBUTION TO C14-LABELLED-DDT IN THE CENTRAL NERVOUS SYSTEM OF CATS].

Authors:  U SCHWABE
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1965-02-02

2.  Insecticide residues in two turtle species following treatment with DDT.

Authors:  P J Owen; M R Wells
Journal:  Bull Environ Contam Toxicol       Date:  1976-04       Impact factor: 2.151

3.  DDT: Inhibition of an ATP-ase in the rat brain.

Authors:  F Matsumura; T A Bratkowski; K C Patil
Journal:  Bull Environ Contam Toxicol       Date:  1969-09       Impact factor: 2.151

4.  Organochlorine pesticide residues associated with mortality: additivity of chlordane and endrin.

Authors:  J L Ludke
Journal:  Bull Environ Contam Toxicol       Date:  1976-09       Impact factor: 2.151

5.  Relationship between lindane concentration in blood and brain and convulsant response in rats after oral or intraperitoneal administration.

Authors:  J M Tusell; C Suñol; E Gelpí; E Rodríguez-Farré
Journal:  Arch Toxicol       Date:  1987-08       Impact factor: 5.153

6.  Response of different-age mallards to DDT.

Authors:  M Friend; D O Trainer
Journal:  Bull Environ Contam Toxicol       Date:  1974-01       Impact factor: 2.151

7.  Accumulation of chlorine-36 ring-labeled DDT residues in various tissues of two species of shrew.

Authors:  D J Forsyth; T J Peterle
Journal:  Arch Environ Contam Toxicol       Date:  1973-02       Impact factor: 2.804

8.  The effect of liver damage on the storage of P,P'-DDT in the rat.

Authors:  D L Grant; W E Phillips
Journal:  Bull Environ Contam Toxicol       Date:  1972-05       Impact factor: 2.151

9.  Penetration of the blood-brain-cerebral spinal fluid barrier by DDT.

Authors:  G Morrison
Journal:  Bull Environ Contam Toxicol       Date:  1971 Jan-Feb       Impact factor: 2.151

10.  Effect of acetylcholine acetyl-hydrolase (E.C. 3.1.1.7) inhibition on the accumulation of pp' DDT in various brain regions of rats.

Authors:  M A Matin; R Agarwal
Journal:  Experientia       Date:  1982-05-15
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