Literature DB >> 14077031

ACTINOMYCIN D: ITS EFFECT ON ANTIBODY FORMATION IN VITRO.

J W UHR.   

Abstract

The formation of antibodies to bacteriophage T(2) in vitro was inhibited by 5 X 10(-8)M actinomycin D. This result is consistent with the concept that antibody formation depends upon DNA-dependent RNA synthesis.

Entities:  

Keywords:  ACTINOMYCIN; ANTIBODY FORMATION; COLIPHAGES; EXPERIMENTAL LAB STUDY; RNA, BACTERIAL

Mesh：

Substances：

Year:  1963        PMID： 14077031     DOI： 10.1126/science.142.3598.1476

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  15 in total

1.  STUDIES ON THE SUPPRESSION OF IMMUNE RESPONSES BY THE PERIWINKLE ALKALOIDS VINCRISTINE AND VINBLASTINE.

Authors:  A C AISENBERG; B WILES
Journal:  J Clin Invest       Date:  1964-12       Impact factor: 14.808

2.  IN VITRO SECONDARY 19S AND 7S ANTIBODY RESPONSES TO POLIOVIRUS IN MEMBRANE CULTURES OF SEPARATED SPLEEN CELLS.

Authors:  S E SVEHAG
Journal:  Arch Gesamte Virusforsch       Date:  1965

3.  Kinetics of antibody production by single cells. II. The action of transcription and translation inhibitors upon the metabolism of haemolysin-secreting cells.

Authors:  J Weyer; A E Bussard
Journal:  Immunology       Date:  1972-06       Impact factor: 7.397

Review 4.  Suppression of the immune response.

Authors:  J Bradley; C J Elson
Journal:  J Med Genet       Date:  1971-09       Impact factor: 6.318

5.  Recovery of anaphylactic sensitivity in the guinea-pig ileum after desensitization.

Authors:  M M Dale; D T Okpako
Journal:  Immunology       Date:  1969-11       Impact factor: 7.397

6.  Enhancement of antibody production after treatment with actinomycin-D: interrelationships between 7S and 19S antibody.

Authors:  J Dobbs; I Rivero; F Sabb; S L Lee
Journal:  Immunology       Date:  1968-02       Impact factor: 7.397

Review 7.  Symposium on in vitro studies of the immune response. IV. Role of nucleic acids in the anamnestic antibody response.

Authors:  A B Stavitsky; J P Gusdon
Journal:  Bacteriol Rev       Date:  1966-06

8.  The effect of Streptomycin on antibody synthesis in vitro.

Authors:  R G Krueger
Journal:  Proc Natl Acad Sci U S A       Date:  1965-07       Impact factor: 11.205

9.  [Antibody synthesis in vitro. II. Stimulation of a cell-free system].

Authors:  D Jacherts
Journal:  Z Med Mikrobiol Immunol       Date:  1966

10.  Primary antibody response studied by using inhibitors of nucleic acid synthesis.

Authors:  L Jarosková; J Mĕstecký; J Sterzl
Journal:  Folia Microbiol (Praha)       Date:  1966       Impact factor: 2.099
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