| Literature DB >> 14075712 |
B CHANDLER, M HAYASHI, M N HAYASHI, S SPIEGELMAN.
Abstract
Electron micrographs of purified replicating form DNA of the bacteriophage øX-174 show that it has ring structure. The circular property may explain both the abnormally high sedimentation coefficient and the great resistance of this DNA to irreversible heat denaturation. Intactness of the circle is required for the control of strand selection during transcription into complementary copies of RNA.Entities:
Keywords: CHEMISTRY; COLIPHAGES; DNA, VIRAL; EXPERIMENTAL LAB STUDY; MICROSCOPY, ELECTRON
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Year: 1964 PMID: 14075712 DOI: 10.1126/science.143.3601.47
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728