| Literature DB >> 14075704 |
Abstract
Injection of sublethal doses of Nembutal (sodium pentobarbital) into deer mice, Peromyscus maniculatus rufinus (Merriam), at diflerent times in their daily activity cycle revealed large differences in rates of recovery. By taking the phase of the circadian rhythm into account, the accuracy obtained in pharmaceutical and physiological bioassays could be increased.Entities:
Keywords: BIOLOGICAL ASSAY; EXPERIMENTAL LAB STUDY; MICE; PENTOBARBITAL; PERIODICITY
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Year: 1963 PMID： 14075704 DOI： 10.1126/science.142.3600.1682
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728