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Literature DB >> 14075687

CLEARANCE OF BACTERIA BY THE LOWER RESPIRATORY TRACT.

G A LAURENZI, J J GUARNERI, R B ENDRIGA, J P CAREY.

Abstract

The disappearance of inhaled bacteria from the lungs of mice is rapid and predictable over an 8-hour period following pulmonary implantation by an aerosol. This indicates that important clearance mechanisms are active in the bronchopulmonary tree. The constant pattern of clearance offers an experimental system in which the effects of various conditions relevant to respiratory infection can be estimated quantitatively. Herein, the effects of hypoxia, alcohol, cigarette smoke, and cortisone are described.

Entities: Chemical Disease Species

Keywords: AEROSOLS; AIR MICROBIOLOGY; ALCOHOL, ETHYL; ANOXIA; BRONCHI; CORTISONE; EXPERIMENTAL LAB STUDY; LUNG; MICE; PHARMACOLOGY; SMOKING; STAPHYLOCOCCUS

Mesh：

Substances：
Aerosols
Ethanol
Cortisone

Year: 1963 PMID： 14075687 DOI： 10.1126/science.142.3599.1572

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

Keyword Cloud
Cited

17 in total

1. Identification of an autophagy defect in smokers' alveolar macrophages.

Authors: Martha M Monick; Linda S Powers; Katherine Walters; Nina Lovan; Michael Zhang; Alicia Gerke; Sif Hansdottir; Gary W Hunninghake
Journal: J Immunol Date: 2010-10-04 Impact factor: 5.422

Review 2. Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factors.

Authors: John Karavitis; Elizabeth J Kovacs
Journal: J Leukoc Biol Date: 2011-08-30 Impact factor: 4.962

Review 3. A brief review of pulmonary clearance of bacterial aerosols emphasizing aspects of particular relevance to veterinary medicine.

Authors: R G Thomson; F Gilka
Journal: Can Vet J Date: 1974-04 Impact factor: 1.008

Review 4. The bovine respiratory disease complex.

Authors: L E Lillie
Journal: Can Vet J Date: 1974-09 Impact factor: 1.008

Review 5. Pathology and pathogenesis of the common diseases of the respiratory tract of cattle.

Authors: R G Thomson
Journal: Can Vet J Date: 1974-09 Impact factor: 1.008

6. Some recent advances in the prevention and treatment of chronic bronchitis and related disorders with special reference to the effects of cigarette smoking.

Authors: C M Fletcher
Journal: Proc R Soc Med Date: 1965-11

CLEARANCE OF BACTERIA BY THE LOWER RESPIRATORY TRACT.

1. Identification of an autophagy defect in smokers' alveolar macrophages.

Review 2. Macrophage phagocytosis: effects of environmental pollutants, alcohol, cigarette smoke, and other external factors.

Review 3. A brief review of pulmonary clearance of bacterial aerosols emphasizing aspects of particular relevance to veterinary medicine.

Review 4. The bovine respiratory disease complex.

Review 5. Pathology and pathogenesis of the common diseases of the respiratory tract of cattle.

6. Some recent advances in the prevention and treatment of chronic bronchitis and related disorders with special reference to the effects of cigarette smoking.

7. Mechanisms of antibacterial action in the respiratory system.

8. Measurement of different mechanisms for elimination of bacteria from the lung.

Review 9. Alcohol and airways function in health and disease.

10. The pulmonary clearance of bacteria by calves and mice.