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Literature DB >> 1407275

Quantitative aspects of reactive gliosis: a review.

W T Norton¹, D A Aquino, I Hozumi, F C Chiu, C F Brosnan.

Abstract

Recent studies of gliosis in a variety of animal models are reviewed. The models include brain injury, neurotoxic damage, genetic diseases and inflammatory demyelination. These studies show that reactive gliosis is not a stereotypic response, but varies widely in duration, degree of hyperplasia, and time course of expression of GFAP immunostaining, content and mRNA. We conclude that there are different biological mechanisms for induction and maintenance of reactive gliosis, which, depending on the kind of tissue damage, result in different expressions of the gliotic response.

Entities: Disease Gene

Mesh：

Year: 1992 PMID： 1407275 DOI： 10.1007/bf00993263

Source DB: PubMed Journal: Neurochem Res ISSN： 0364-3190 Impact factor: 3.996

72 in total

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100 in total

1. Differential expression of small heat shock proteins in reactive astrocytes after focal ischemia: possible role of beta-adrenergic receptor.

Authors: T Imura; S Shimohama; M Sato; H Nishikawa; K Madono; A Akaike; J Kimura
Journal: J Neurosci Date: 1999-11-15 Impact factor: 6.167

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Authors: Shinrye Lee; Eunha Jang; Jong-Heon Kim; Jae-Hong Kim; Won-Ha Lee; Kyoungho Suk
Journal: J Biol Chem Date: 2012-01-24 Impact factor: 5.157

4. EphA4 deficient mice maintain astroglial-fibrotic scar formation after spinal cord injury.

Authors: Julia E Herrmann; Ravi R Shah; Andrea F Chan; Binhai Zheng
Journal: Exp Neurol Date: 2010-02-17 Impact factor: 5.330

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Authors: Gary A Weisman; M Wang; Q Kong; N E Chorna; J T Neary; Grace Y Sun; Fernando A González; C I Seye; L Erb
Journal: Mol Neurobiol Date: 2005 Impact factor: 5.590

6. Reactive changes of retinal astrocytes and Müller glial cells in kainate-induced neuroexcitotoxicity.

Authors: Min-Lin Chang; Ching-Hsiang Wu; Ya-Fen Jiang-Shieh; Jeng-Yung Shieh; Chen-Yuan Wen
Journal: J Anat Date: 2007-01 Impact factor: 2.610

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Authors: Mausam Ghosh; Sumantra Das
Journal: Cell Mol Neurobiol Date: 2007-09-08 Impact factor: 5.046