Literature DB >> 1407267

Comparative study between 4-aminobutyrate-2-oxoglutarate aminotransferase (GABA-T) from rat forebrain and cerebellum.

C Arce1, S Cañadas, M De Vicente, M J Oset-Gasque, M P González.   

Abstract

In this study differences in the biochemical properties of 4-aminobutyric acid aminotransferase (GABA-T) from forebrain and cerebellum were detected. These differences may be related to: a) the characteristics of the catalytic site, b) the substrate affinities and c) their pyridoxal-phosphate requirements which suggests that PLP could be a physiological regulator of these forms of brain GABA-T.

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Year:  1992        PMID: 1407267     DOI: 10.1007/bf00968009

Source DB:  PubMed          Journal:  Neurochem Res        ISSN: 0364-3190            Impact factor:   3.996


  17 in total

1.  Further evidence for the existence of isozymes of brain gamma-aminobutyrate aminotransferase.

Authors:  T T Ngo; G Tunnicliff
Journal:  Comp Biochem Physiol C Comp Pharmacol       Date:  1978

2.  Differential effects of n-dipropylacetate and amino-oxyacetic acid on gamma-aminobutyric acid levels in discrete areas of rat brain.

Authors:  M J Iadarola; A Raines; K Gale
Journal:  J Neurochem       Date:  1979-11       Impact factor: 5.372

3.  A -aminobutyrate pathway in mammalian kidney cortex.

Authors:  G Lancaster; F Mohyuddin; C R Scriver; D T Whelan
Journal:  Biochim Biophys Acta       Date:  1973-02-28

4.  Identification of multiple forms of aminobutyrate transaminase in mouse and rat brain: subcellular localization.

Authors:  A Waksman; M Bloch
Journal:  J Neurochem       Date:  1968-02       Impact factor: 5.372

Review 5.  The pharmacology of GABA-transaminase inhibitors.

Authors:  M G Palfreyman; P J Schechter; W R Buckett; G P Tell; J Koch-Weser
Journal:  Biochem Pharmacol       Date:  1981-04-15       Impact factor: 5.858

6.  Method of assay for 4-aminobutyrate-2-oxoglutarate aminotransferase.

Authors:  M P González; S Cañadas; F Muñoz; J Sánchez-Prieto; V Morales
Journal:  Rev Esp Fisiol       Date:  1983-06

7.  GABA-T in bovine medulla cells: kinetic properties and comparison with GABA-T from other tissues.

Authors:  J M Fernández-Ramil; J Sánchez-Prieto; S Cañadas; M P González
Journal:  Rev Esp Fisiol       Date:  1983-09

8.  Activation of aposerine transhydroxymethylase by pyridoxal-5'-phosphate monomethyl ester.

Authors:  L Schirch; K D Schnackerz
Journal:  Biochem Biophys Res Commun       Date:  1978-11-14       Impact factor: 3.575

9.  Immunocytochemical localization of gamma-aminobutyric acid transaminase at cellular and ultrastructural levels.

Authors:  V Chan-Palay; J Y Wu; S L Palay
Journal:  Proc Natl Acad Sci U S A       Date:  1979-04       Impact factor: 11.205

10.  Two forms of rat brain glutamic acid decarboxylase differ in their dependence on free pyridoxal phosphate.

Authors:  L A Denner; J Y Wu
Journal:  J Neurochem       Date:  1985-03       Impact factor: 5.372

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