Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 PROTEIN POLYSACCHARIDE IN CONNECTIVE TISSUE: INHIBITION OF PHASE SEPARATION.

Literature DB >> 14072176

PROTEIN POLYSACCHARIDE IN CONNECTIVE TISSUE: INHIBITION OF PHASE SEPARATION.

Abstract

A macromolecule of protein and chondroitin sulfate (PP-L) inhibits sedimentation of barium-polystyrene sulfonate (BaPSS) and of calcium phosphate at low but not at high values of gravity. Sedimentation of BaPSS removes a large fraction of PP-L from solution, but sedimentation of calcium phosphate does not. The results suggest entanglement among linear polyanionic chains.

Entities: Chemical Gene

Keywords: CHEMISTRY; CHONDROITIN; CONNECTIVE TISSUE; EXPERIMENTAL LAB STUDY; PHOSPHATES; PROTEINS; SULFONIC ACIDS

Mesh：

Substances：

Year: 1963 PMID： 14072176 DOI： 10.1126/science.142.3595.1073

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

Keyword Cloud
Cited

9 in total

1. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen.

Authors: M Alini; Y Matsui; G R Dodge; A R Poole
Journal: Calcif Tissue Int Date: 1992-04 Impact factor: 4.333

2. Relationship between pyrophosphate, amorphous calcium phosphate and other factors in the sequence of calcification in vivo.

Authors: R E Wuthier; S Bisaz; R G Russell; H Fleisch
Journal: Calcif Tissue Res Date: 1972

3. Inhibition of calcium phosphate mineral growth by proteoglycan aggregate fractions in a synthetic lymph.

Authors: L A Cuervo; J C Pita; D S Howell
Journal: Calcif Tissue Res Date: 1973

4. Demonstration of macromolecular inhibitors of calcification and nucleational factors in fluid from calcifying sites in cartilage.

Authors: D S Howell; J C Pita; J F Marquez; R A Gatter
Journal: J Clin Invest Date: 1969-04 Impact factor: 14.808

PROTEIN POLYSACCHARIDE IN CONNECTIVE TISSUE: INHIBITION OF PHASE SEPARATION.

1. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen.

2. Relationship between pyrophosphate, amorphous calcium phosphate and other factors in the sequence of calcification in vivo.

3. Inhibition of calcium phosphate mineral growth by proteoglycan aggregate fractions in a synthetic lymph.

4. Demonstration of macromolecular inhibitors of calcification and nucleational factors in fluid from calcifying sites in cartilage.

5. Alkaline phosphatase and peptidase levels in invertebrate cartilage.

6. The glycosaminoglycans of human plasma.

7. Effects of chondroitin sulphates on mineralization in vitro.

8. Evidence for a role of proteinpolysaccharides in regulation of mineral phase separation in calcifying cartilage.

9. Role of proteoglycans in endochondral ossification: inhibition of calcification.