Literature DB >> 14069228

ACTINOMYCIN D: SPECIFIC INHIBITORY EFFECTS ON THE EXPLANTED CHICK EMBRYO.

N W KLEIN, L J PIERRO.   

Abstract

Chick embryos containing 11 to 13 somites were cultured for 48 hours on media containing various amounts of the antibiotic actinomycin D. Morphological observations as well as quantitative determinations of protein nitrogen, DNA, and RNA indicate that the antibiotic specifically inhibits the growth and development of the embryonic axis posterior to the 12th somite.

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Keywords:  ACTINOMYCIN; CHICK EMBRYO; EXPERIMENTAL LAB STUDY; PHARMACOLOGY; TOXICOLOGIC REPORT

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Year:  1963        PMID: 14069228     DOI: 10.1126/science.142.3594.967

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  2 in total

1.  Effects of actinomycin D on nucleic acid metabolism and protein biosynthesis during metamorphosis of Tenebrio molitor L.

Authors:  J Ilan; J H Quastel
Journal:  Biochem J       Date:  1966-08       Impact factor: 3.857

2.  The differential sensitivity of cultured chick mesodermal cells to actinomycin D.

Authors:  J A Piper; N W Klein
Journal:  J Cell Biol       Date:  1969-01       Impact factor: 10.539

  2 in total

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