Literature DB >> 14068232

ANTIBACTERIAL AND ENZYMIC BASIC PROTEINS FROM LEUKOCYTE LYSOSOMES: SEPARATION AND IDENTIFICATION.

H I ZEYA, J K SPITZNAGEL.   

Abstract

A lysosomal fraction from polymorphonuclear leukocytes has been directly analyzed for basic proteins by zone electrophoresis. Evidence for the presence of bactericidal basic proteins in polymorphonuclear leukocyte lysosomes is presented.

Keywords:  ARGININE; BACTERIA; CYTOLOGY; ELECTROPHORESIS; LEUKOCYTES; MURAMIDASE; PROTEINS; RIBONUCLEASE

Mesh：

Substances：

Year:  1963        PMID： 14068232     DOI： 10.1126/science.142.3595.1085

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  63 in total

1.  The defensin receptor: a possible mechanism responsible for reduced excitability of the neuronal sensory membrane.

Authors:  I V Rogachevskii; V B Plakhova; B F Shchegolev; A D Nozdrachev; B V Krylov; S A Podzorova; V N Kokryakov
Journal:  Dokl Biol Sci       Date:  2000 Nov-Dec

2.  Inhibition of leucocytic lysosomal enzymes by glycosaminoglycans in vitro.

Authors:  J L Avila; J Convit
Journal:  Biochem J       Date:  1975-10       Impact factor: 3.857

3.  Physicochemical characteristics of the glycosaminoglycan-lysosomal enzyme interaction in vitro. A model of control of leucocytic lysosomal activity.

Authors:  J L Avila; J Convit
Journal:  Biochem J       Date:  1976-11-15       Impact factor: 3.857

4.  Cationic polyelectrolytes from leukocytes might kill bacteria by activating their autolytic systems: enigmatically, the relevance of this phenomenon to post-infectious sequelae is disregarded.

Authors:  Isaac Ginsburg
Journal:  Intensive Care Med       Date:  2002-08       Impact factor: 17.440

5.  Defensins and other antimicrobial peptides at the ocular surface.

Authors:  Alison M McDermott
Journal:  Ocul Surf       Date:  2004-10       Impact factor: 5.033

6.  A possible molecular mechanism for the interaction of defensin with the sensory neuron membrane.

Authors:  V B Plakhova; B F Shchegolev; I V Rogachevskii; A D Nozdrachev; B V Krylov; S A Podzorova; V N Kokryakov
Journal:  Neurosci Behav Physiol       Date:  2002 Jul-Aug

7.  Cationic antimicrobial proteins isolated from human neutrophil granulocytes in the presence of diisopropyl fluorophosphate.

Authors:  W M Shafer; L E Martin; J K Spitznagel
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

Review 8.  The roles of antimicrobial peptides in innate host defense.

Authors:  Gill Diamond; Nicholas Beckloff; Aaron Weinberg; Kevin O Kisich
Journal:  Curr Pharm Des       Date:  2009       Impact factor: 3.116

9.  Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity.

Authors:  R I Lehrer; A Barton; K A Daher; S S Harwig; T Ganz; M E Selsted
Journal:  J Clin Invest       Date:  1989-08       Impact factor: 14.808

10.  In vitro activity of the antimicrobial peptides human and rabbit defensins and porcine leukocyte protegrin against Mycobacterium tuberculosis.

Authors:  Y Miyakawa; P Ratnakar; A G Rao; M L Costello; O Mathieu-Costello; R I Lehrer; A Catanzaro
Journal:  Infect Immun       Date:  1996-03       Impact factor: 3.441
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