Literature DB >> 14068216

GENETIC ALTERATION OF ADENYLIC PYROPHOSPHORYLASE IN SALMONELLA.

G P KALLE, J S GOTS.   

Abstract

A mutant of Salmonella typhimurium, resistant to inhibition by 2, 6-diaminopurine, differs from its sensitive wild-type parent by an altered adenylic acid pyrophosphorylase. The altered enzyme, though still active with adenine as substrate, is inactive in the conversion of diaminopurine to its nucleotide. It also differs from the wildtype enzyme in a number of physical and chemical properties.

Entities:  

Keywords:  EXPERIMENTAL LAB STUDY; GENETICS; PHOSPHOTRANSFERASES; PURINES; SALMONELLA TYPHIMURIUM

Mesh:

Substances:

Year:  1963        PMID: 14068216     DOI: 10.1126/science.142.3593.680

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  12 in total

1.  PROMOTION OF RETARDATION OF THE GROWTH OF ADENINE AUXOTROPHS OF CANDIDA ALBICANS BY PURINES, PYRIMIDINES AND NUCLEOSIDES.

Authors:  A SARACHEK
Journal:  Antonie Van Leeuwenhoek       Date:  1964       Impact factor: 2.271

2.  Genes conferring resistance to 8-aza adenine in Neurospora crassa and the variability of resistant alleles in the aza-1 locus with respect to excretion of purines.

Authors:  K K Jha
Journal:  Mol Gen Genet       Date:  1972

3.  Dependence of diaminopurine utilization on the mutational site of purine auxotrophy in Bacillus subtilis. II. Tracer experiments.

Authors:  H T Shigeura; A L Demain
Journal:  J Bacteriol       Date:  1968-02       Impact factor: 3.490

4.  The substrate specificity of purine phosphoribosyltransferases in Schizosaccharomyces pombe.

Authors:  A De Groodt; E P Whitehead; H Heslot; L Poirier
Journal:  Biochem J       Date:  1971-05       Impact factor: 3.857

5.  Escherichia coli mutants deficient in guanine-xanthine phosphoribosyltransferase.

Authors:  J A Holden; P D Harriman; J D Wall
Journal:  J Bacteriol       Date:  1976-06       Impact factor: 3.490

6.  Mitochondrial activity of 2,6-diaminopurine in Saccharomyces cerevisiae.

Authors:  C Wallis; D Wilkie
Journal:  Mol Gen Genet       Date:  1979-06-20

7.  Studies on the pathway of incorporation of 2-aminopurine into the deoxyribonucleic acid of Escherichia coli.

Authors:  E G Rogan; M J Bessman
Journal:  J Bacteriol       Date:  1970-09       Impact factor: 3.490

8.  Utilization of 2,6-diaminopurine by Salmonella typhimurium.

Authors:  B B Garber; J S Gots
Journal:  J Bacteriol       Date:  1980-08       Impact factor: 3.490

9.  Genetic separation of hypoxanthine and guanine-xanthine phosphoribosyltransferase activities by deletion mutations in Salmonella typhimurium.

Authors:  J S Gots; C E Benson; S R Shumas
Journal:  J Bacteriol       Date:  1972-11       Impact factor: 3.490

10.  Adenine phosphoribosyltransferase in Mycoplasma mycoides and Escherichia coli.

Authors:  I L Sin; L R Finch
Journal:  J Bacteriol       Date:  1972-10       Impact factor: 3.490

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