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Literature DB >> 140675

Transmural distribution of myocardial blood flow and of coronary reserve in canine left ventricular hypertrophy.

J Holtz, W V Restorff, P Bard, E Bassenge.

Abstract

Left ventricular hypertrophy was induced by banding of the ascending aorta in pupies at the age of 6 weeks. At the age of one year left ventricular weight per body weight was increased by 87% compared to control litter mates. While myocardial perfusion and myocardial oxygen consumption per 100 g were identical in the hypertrophy and control group, there was a significantly diminshed ratio of subendocardial/subepicardial flow in the hypertrophy group during moderate exercise. With maximal coronary dilation subendocardial diastolic resistance (mm Hg/ml-min-1 per 100 g) was 0.16 +/- 0.03 in the control group and 0.26 +/- 0.03 in the hypertrophy group. This diminished coronary reserve indicates an insufficient growth of the vascular bed in these hypertrophied hearts.

Entities: Chemical Disease Species

Mesh：

Year: 1977 PMID： 140675 DOI： 10.1007/bf01906375

Source DB: PubMed Journal: Basic Res Cardiol ISSN： 0300-8428 Impact factor: 17.165

12 in total

1. Uniformity of transmural perfusion in anesthetized dogs with maximally dilated coronary circulations.

Authors: H F Downey; F A Bashour; R B Boatwright; P E Parker; S J Kechejian
Journal: Circ Res Date: 1975-07 Impact factor: 17.367

2. Cardiac performance in ventricular hypertrophy induced by pressure and volume overloading.

Authors: A B Malik; T Abe; H O O'Kane; A S Geha
Journal: J Appl Physiol Date: 1974-12 Impact factor: 3.531

3. Cardiac function, coronary flow, and oxygen consumption in stable left ventricular hypertrophy.

Authors: A B Malik; T Abe; H O'kane; A S Geha
Journal: Am J Physiol Date: 1973-07

4. Ventricular performance, coronary flow, and MVO 2 in aortic coarctation hypertrophy.

Authors: W J Gamble; C Phornphutkul; A E Kumar; G L Sanders; F J Manasek; R G Monroe
Journal: Am J Physiol Date: 1973-04

5. Capacity of the terminal vascular bed during normal growth, in cardiomegaly, and in cardiac atrophy.

Authors: K Rakusan; W du Mesnil de Rochemont; W Braasch; H Tschopp; R J Bing
Journal: Circ Res Date: 1967-08 Impact factor: 17.367

6. Distribution of the coronary blood flow across the canine heart wall during systole.

Authors: J M Downey; E S Kirk
Journal: Circ Res Date: 1974-02 Impact factor: 17.367

7. Transmural differences in myocardial blood flow and in coronary dilatory capacity in hemodiluted conscious dogs.

Authors: J Holtz; E Bassenge; W von Restoriff; E Mayer
Journal: Basic Res Cardiol Date: 1976 Jan-Feb Impact factor: 17.165

8. Quantification of collateral resistance in acute and chronic experimental coronary occlusion in the dog.

Authors: W Schaper; W Flameng; B Winkler; B Wüsten; W Türschmann; G Neugebauer; M Carl; S Pasyk
Journal: Circ Res Date: 1976-09 Impact factor: 17.367

9. Transmural distribution of myocardial blood flow during systole in the awake dog.

Authors: D S Hess; R J Bache
Journal: Circ Res Date: 1976-01 Impact factor: 17.367

10. Transmural gradients in ventricular tissue metabolites produced by stopping coronary blood flow in the dog.

Authors: R B Dunn; D M Griggs
Journal: Circ Res Date: 1975-10 Impact factor: 17.367

22 in total

1. Development and reversal of pressure-induced cardiac hypertrophy. Light and electron microscopic study in the rat under temporary aortic constriction.

Authors: P Y Hatt; P Jouannot; J Moravec; J Perennec; M Laplace
Journal: Basic Res Cardiol Date: 1978 Sep-Oct Impact factor: 17.165

2. Tl-201 washout rate in remote normal regions in patients with prior myocardial infarction and left ventricular remodeling.

Authors: Toshihiko Goto; Nobuyuki Ohte; Hiromichi Miyabe; Seiji Mukai; Seiichiro Sakata; Junichiro Hayano; Genjiro Kimura
Journal: J Nucl Cardiol Date: 2005 Mar-Apr Impact factor: 5.952

3. Impaired myocardial oxidative metabolism in the remote normal region in patients in the chronic phase of myocardial infarction and left ventricular remodeling.

Authors: Nobuyuki Ohte; Hitomi Narita; Akihiko Iida; Kazuaki Wakami; Kaoru Asada; Hidekatsu Fukuta; Takafumi Kato; Junichiro Hyano; Genjiro Kimura
Journal: J Nucl Cardiol Date: 2009-01-20 Impact factor: 5.952

4. Left ventricular remodeling after myocardial infarction impairs early diastolic, but not systolic, function in the radial direction in the remote normal region.

Authors: Hiroko Kobayakawa; Nobuyuki Ohte; Kazuaki Wakami; Hidekatsu Fukuta; Toshihiko Goto; Tomomitsu Tani; Hitomi Narita; Genjiro Kimura
Journal: J Echocardiogr Date: 2010-07-31

5. Demonstration of alpha-adrenergic coronary control in different layers of canine myocardium by regional myocardial sympathectomy.

Authors: J Holtz; E Mayer; E Bassenge
Journal: Pflugers Arch Date: 1977-12-12 Impact factor: 3.657

Review 6. Pulmonary hypertension.

Authors: J R Michael; W R Summer
Journal: Lung Date: 1985 Impact factor: 2.584

7. Intracapillary hemoglobin oxygen saturation and oxygen consumption in different layers of the left ventricular myocardium.

Authors: J Holtz; W A Grunewald; R Manz; W von Restorff; E Bassenge
Journal: Pflugers Arch Date: 1977-09-16 Impact factor: 3.657