Literature DB >> 14066152

BALANCED INCOMPLETE BLOCK DESIGNS IN BIOLOGICAL ASSAY ILLUSTRATED BY THE ASSAY OF GASTRIN USING A YOUDEN SQUARE.

D COLQUHOUN.   

Abstract

General equations are given for computing the results of any (j+j) dose parallel line biological assay based on an incomplete block design. Only the information from comparisons within blocks is used. The computation is illustrated numerically by means of a (2+2) assay of gastrin devised and performed by Lai (1962), in which only three of the four doses could be given to each animal.

Entities:  

Keywords:  BIOLOGICAL ASSAY; EXPERIMENTAL LAB STUDY; GASTRIN; RATS

Mesh:

Substances:

Year:  1963        PMID: 14066152      PMCID: PMC1703851          DOI: 10.1111/j.1476-5381.1963.tb01502.x

Source DB:  PubMed          Journal:  Br J Pharmacol Chemother        ISSN: 0366-0826


  4 in total

1.  The binding of labelled tetrodotoxin to non-myelinated nerve fibres.

Authors:  D Colquhoun; R Henderson; J M Ritchie
Journal:  J Physiol       Date:  1972-12       Impact factor: 5.182

2.  Effects of SC 15396 on gastric secretion. 3. The action in the rat.

Authors:  C G Thomson; W Sircus
Journal:  Gut       Date:  1968-12       Impact factor: 23.059

3.  Rapid histamine assays: a method and some theoretical considerations.

Authors:  D Colquhoun; M L Tattersall
Journal:  Br J Pharmacol       Date:  1970-01       Impact factor: 8.739

4.  STUDIES ON GASTRIN.

Authors:  S K LAI
Journal:  Gut       Date:  1964-08       Impact factor: 23.059

  4 in total

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