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Literature DB >> 14064449

LONG-TERM ISOLATION STRESS IN RATS.

Abstract

Rats isolated for long periods became nervous and aggressive and developed caudal dermatitis ( scaly tail). After 13 weeks of isolation, rats had heavier adrenals and thyroid and lighter spleen and thymus compared with rats kept in community cages. This indicates an endocrinopathy with hyperfunction of the adrenal cortex.

Entities: Disease Species

Keywords: ADRENAL GLAND HYPERFUNCTION; DERMATITIS; EXPERIMENTAL LAB STUDY; LIVER GLYCOGEN; RATS; SPLEEN; STRESS; THYROID GLAND

Mesh：

Substances：
Liver Glycogen

Year: 1963 PMID： 14064449 DOI： 10.1126/science.142.3591.507

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

17 in total

1. Effects of two kinds of social deprivation on testosterone and estradiol-17 beta plasma levels in the male rat.

Authors: F Dessì-Fulgheri; C L di Prisco; P Verdarelli
Journal: Experientia Date: 1976-01-15

2. Effect of sodium hydroxybutyrate on behavior of mice after prolonged isolation.

Authors: M Krsiak; D Novakova; I Paclt; R U Ostrovskaya
Journal: Bull Exp Biol Med Date: 1974-09 Impact factor: 0.804

3. Effects of isolation on maternal aggressiveness and body growth rates of offspring.

Authors: A S Weltman; A M Sackler; R Schwartz; S Stroman
Journal: Experientia Date: 1967-09-15

4. Evaluation of Treatment Options for Ulcerative Dermatitis in the P Rat.

Authors: Beth A Skiles; Chris A Boehm; Jessica L Peveler; Debra L Hickman
Journal: J Am Assoc Lab Anim Sci Date: 2021-05-03 Impact factor: 1.232

5. Free choice ethanol intake of laboratory rats under different social conditions.

Authors: J Wolffgramm
Journal: Psychopharmacology (Berl) Date: 1990 Impact factor: 4.530

Review 6. Myocardial diseases of animals.

Authors: J F Van Vleet; V J Ferrans
Journal: Am J Pathol Date: 1986-07 Impact factor: 4.307

LONG-TERM ISOLATION STRESS IN RATS.

1. Effects of two kinds of social deprivation on testosterone and estradiol-17 beta plasma levels in the male rat.

2. Effect of sodium hydroxybutyrate on behavior of mice after prolonged isolation.

3. Effects of isolation on maternal aggressiveness and body growth rates of offspring.

4. Evaluation of Treatment Options for Ulcerative Dermatitis in the P Rat.

5. Free choice ethanol intake of laboratory rats under different social conditions.

Review 6. Myocardial diseases of animals.

7. Effect of photoperiod and all-female grouping on the estrous cycle of the bandicoot rat, Bandicota bengalensis.

8. Behavioral, metabolic, and renal outcomes of 1-month isolation in adolescent male Dahl salt-sensitive rats.

9. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress.

10. Social reinforcement of operant behavior in rats: a methodological note.