Literature DB >> 14063328

TWO CASES OF THROMBOHAEMOLYTIC THROMBOCYTOPENIC PURPURA ASSOCIATED WITH CHANGES IN RED CELL MORPHOLOGY.

P MCCORMACK, D J O'BRIEN, R A OLIVER.   

Abstract

Two adult cases of thrombohaemolytic thrombocytopenic purpura are described. Both showed striking morphological changes in the red cells with increased saline osmotic fragility, in addition to thrombocytopenia and generalized hyaline thrombi affecting small blood vessels. These changes support the hypothesis that this is a triple auto-immune disorder affecting red cells, platelets, and small blood vessels.

Entities:  

Keywords:  ERYTHROCYTES; PATHOLOGY; PURPURA, THROMBOPENIC

Mesh:

Year:  1963        PMID: 14063328      PMCID: PMC480604          DOI: 10.1136/jcp.16.5.436

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  7 in total

1.  Microangiopathic haemolytic anaemia: the possible role of vascular lesions in pathogenesis.

Authors:  M C BRAIN; J V DACIE; D O HOURIHANE
Journal:  Br J Haematol       Date:  1962-10       Impact factor: 6.998

2.  The nature of the hyaline thrombi in thrombotic thrombocytopenic purpura.

Authors:  J M CRAIG; D GITLIN
Journal:  Am J Pathol       Date:  1957 Mar-Apr       Impact factor: 4.307

3.  Thrombotic thrombocytopenic purpura; a hyperergic micro-angiopathy.

Authors:  A E STUART; G MACGREGOR-ROBERTSON
Journal:  Lancet       Date:  1956-04-21       Impact factor: 79.321

4.  Thrombotic microangiopathy; histological diagnosis during life.

Authors:  W S SYMMERS
Journal:  Lancet       Date:  1956-05-05       Impact factor: 79.321

5.  Hemolytic anemia; direct and indirect indications, pathogenetic mechanisms and classifications.

Authors:  W DAMESHEK
Journal:  Am J Med       Date:  1955-02       Impact factor: 4.965

6.  The transfusion of human blood platelets with a note on the transfusion of granulocytes.

Authors:  E O HIRSCH; F H GARDNER
Journal:  J Lab Clin Med       Date:  1952-04

7.  Thrombotic thrombocytopenic purpura. II. Studies on the hemolytic syndrome in this disease.

Authors:  K SINGER; A G MOTULSKY; J N SHANBERGE
Journal:  Blood       Date:  1950-05       Impact factor: 22.113

  7 in total
  1 in total

1.  Thrombotic thrombocytopenic purpura: successful treatment of two cases.

Authors:  J Schwartz; A Rosenberg; A A Cooperberg
Journal:  Can Med Assoc J       Date:  1972-06-10       Impact factor: 8.262

  1 in total

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