| Literature DB >> 14052974 |
Abstract
Four patients were observed who developed similar episodes of peripheral neuropathy following prolonged treatment with chloroquine phosphate. This previously unreported toxic reaction consisted of bilateral loss of knee and ankle reflexes and weakness of the quadriceps muscles. Gradual return to normal followed withdrawal of the chloroquine. Other toxic reactions to the drug are reviewed.Entities:
Keywords: ARTHRITIS, RHEUMATOID; CHLOROQUINE; GERIATRICS; PERIPHERAL NERVE DISEASES; TOXICOLOGIC REPORT
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Year: 1963 PMID： 14052974 PMCID： PMC1921850
Source DB: PubMed Journal: Can Med Assoc J ISSN： 0008-4409 Impact factor: 8.262