| Literature DB >> 14047630 |
P L PILLSBURY, J A CHRISTENSEN.
Abstract
In a study utilizing an alternating double blind technique 15 patients were given alphamethyldopa in divided doses of 1 gram daily alone and in combination with a benzothiadiazine diuretic. The average blood pressure of patients receiving the drug alone was 157/90 mm of mercury, against the placebo control of 195/109 mm. The average blood pressure of patients receiving the drug in combination with a benzothiadiazine diuretic was 164/98 mm; in the control with placebo plus benzothiadiazine diuretic, it was 169/104 mm. Alpha-methyldopa appeared to be effective in reducing blood pressure in patients with benign essential hypertension.Entities:
Keywords: ANTIHYPERTENSIVE AGENTS; BENZOTHIADIAZINES; HYPERTENSION; METHYLDOPA; PLACEBOS
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Year: 1963 PMID： 14047630 PMCID： PMC1515246
Source DB: PubMed Journal: Calif Med ISSN： 0008-1264