| Literature DB >> 1404620 |
S Barik1.
Abstract
Extracts made from human respiratory syncytial virus (RSV)-infected Hep-2 cells synthesized mRNAs encoded by all known viral genes. In contrast, RSV ribonucleoproteins purified from infected cells failed to transcribe in vitro; transcription was restored by addition of a cytoplasmic extract of uninfected Hep-2 cells, demonstrating that a cellular factor(s) has a role in RSV gene expression. Quantitation of the individual gene mRNAs transcribed in vitro revealed polarity of transcription of the genome.Entities:
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Year: 1992 PMID: 1404620 PMCID: PMC240184
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103