Literature DB >> 14045135

FIXATION OF COMPLEMENT TO FRAGMENTS OF ANTIBODY.

A M REISS, O J PLESCIA.   

Abstract

A specific precipitate of ovalbumin and its rabbit-serum antibody, after fixing human serum complement, was digested with papain. The digest was analyzed immunochemically for complexes of antigen, antibody fragments, and components of complement. The results indicated that complement is not bound to Porter fragment III, but very likely is bound to fragments I and II.

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Keywords:  ANTIGEN-ANTIBODY REACTIONS; CHROMATOGRAPHY; COMPLEMENT FIXATION TESTS; EXPERIMENTAL LAB STUDY; HEAT; IMMUNE SERUMS; IMMUNOELECTROPHORESIS; OVALBUMIN; PAPAIN; RABBITS

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Year:  1963        PMID： 14045135     DOI： 10.1126/science.141.3583.812

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  3 in total

1.  Properties of fragments of human Wassermann antibodies.

Authors:  K Amiraian; E J Leikhim
Journal:  Immunology       Date:  1966-04       Impact factor: 7.397

2.  Induction of antibody synthesis. Effect of blocking defined determinants of an antigen.

Authors:  A Bernardini; S Imperato; O U Plescia
Journal:  Immunology       Date:  1970-02       Impact factor: 7.397

3.  SPECIFIC FRACTIONATION OF HUMAN ANTIDEXTRAN ANTIBODIES. II. ASSAY OF HUMAN ANTIDEXTRAN SERA AND SPECIFICALLY FRACTIONATED PURIFIED ANTIBODIES BY MICROCOMPLEMENT FIXATION AND COMPLEMENT FIXATION INHIBITION TECHNIQUES.

Authors:  J GELZER; E A KABAT
Journal:  J Exp Med       Date:  1964-01-01       Impact factor: 14.307
  3 in total

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