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Literature DB >> 14044038

SYNERGISM BETWEEN SULPHONAMIDE DRUGS AND ANTIBIOTICS OF THE POLYMYXIN GROUP AGAINST PROTEUS SP. IN VITRO.

Abstract

Interesting synergism in vitro between a recently introduced antibiotic, colistin methane sulphonate, and sulphonamide drugs is described. The observations were extended to polymyxin B sulphate and sulphonamides with essentially similar results. The combinations are bactericidal at therapeutic levels, the ratio of drugs to one another is not critical, and the effect is present over a fairly wide pH range.

Entities: Chemical Species

Keywords: COLISTIN; EXPERIMENTAL LAB STUDY; POLYMYXIN; PROTEUS; SULFONAMIDES

Mesh：

Substances：

Year: 1963 PMID： 14044038 PMCID： PMC480577 DOI： 10.1136/jcp.16.4.362

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

4 in total

1. "Colomycin". Laboratory and clinical investigations.

Authors: G TAYLOR; H ALLISON
Journal: Br Med J Date: 1962-07-21

2. Pseudomonas pyocyanea infection treated with colistin methane sulphonate.

Authors: M MCMILLAN; T M PRICE; D M MACLAREN; G W SCOTT
Journal: Lancet Date: 1962-10-13 Impact factor: 79.321

3. The use of colymycin in chronic urinary infections due to Pseudomonas aeuroginosa.

Authors: G CARROLL; W F MALETTE
Journal: J Urol Date: 1961-01 Impact factor: 7.450

4 in total

12 in total

Review 1. Principles of combination therapy.

Authors: S Levin; A A Harris
Journal: Bull N Y Acad Med Date: 1975-10

8. [Combination of bacteriostatic and bactericidal drugs: lack of significant in vitro antagonism between penicillin, cephalothin, and rolitetracycline].

Authors: F D Daschner
Journal: Antimicrob Agents Chemother Date: 1976-11 Impact factor: 5.191

9. Gram-negative bacterial endocarditis in narcotic addicts.

Authors: J E Rosenblatt; J G Dahlgren; R S Fishbach; F P Tally
Journal: Calif Med Date: 1973-02

10. Potentiation of inhibitory activity of colistin on Pseudomonas aeruginosa by sulphamethoxazole and sulphamethizole.

Authors: N A Simmons
Journal: Br Med J Date: 1969-09-20

SYNERGISM BETWEEN SULPHONAMIDE DRUGS AND ANTIBIOTICS OF THE POLYMYXIN GROUP AGAINST PROTEUS SP. IN VITRO.

1. "Colomycin". Laboratory and clinical investigations.

2. Pseudomonas pyocyanea infection treated with colistin methane sulphonate.

3. The use of colymycin in chronic urinary infections due to Pseudomonas aeuroginosa.

Review 1. Principles of combination therapy.

2. In vitro additive effect of polymxin B and rifampin against Serratia marcesen.

3. Inducible high resistance to colistin in Proteus strains.

4. Synergism of polymyxin and sulfonamides in L-forms of Staphylococcus aureus and Proteus mirabilis.

5. Colistin, sulphamethoxazole, and trimethoprim in synergy against Gram-negative bacteria.

6. Sulfamethoxazole-trimethoprim-polymyxin therapy of serious multiply drug-resistant Serratia infections.

7. Combined activity of sulfamethoxazole, trimethoprim, and polymyxin B against gram-negative bacilli.

8. [Combination of bacteriostatic and bactericidal drugs: lack of significant in vitro antagonism between penicillin, cephalothin, and rolitetracycline].

9. Gram-negative bacterial endocarditis in narcotic addicts.

10. Potentiation of inhibitory activity of colistin on Pseudomonas aeruginosa by sulphamethoxazole and sulphamethizole.