Literature DB >> 1404022

Diagonal earlobe creases and atheromatous disease: a postmortem study.

V Patel1, C Champ, P S Andrews, B E Gostelow, N P Gunasekara, A R Davidson.   

Abstract

The association between the grade of earlobe creases and degree of atheromatous disease was investigated in 376 postmortem examinations. Each earlobe crease was individually graded from 0 to 3. The risk of atherosclerosis as a cause of death was nearly doubled in men with grade 3 creases in both earlobes, and more than trebled in women with bilateral high-grade creases. The risk of death from myocardial infarction was 2.50 in men with high-grade creases and 3.70 in women. The earlobe crease is an important sign of atheromatous disease and it may be useful to include it in the clinical examination of patients.

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Year:  1992        PMID: 1404022      PMCID: PMC5375484     

Source DB:  PubMed          Journal:  J R Coll Physicians Lond        ISSN: 0035-8819


  10 in total

Review 1.  Frank's sign and paired ear creases of the helix : Current concepts of significance for morbidity.

Authors:  George S Stoyanov; Deyan Dzhenkov; Lilyana Petkova; Deyana Velkova; Nikolay Sapundzhiev; Peter Ghenev
Journal:  Wien Klin Wochenschr       Date:  2021-11-24       Impact factor: 1.704

Review 2.  Diagonal ear lobe crease and atherosclerosis: a review of the medical literature and dental implications.

Authors:  Arthur H Friedlander; José López-López; Eugenio Velasco-Ortega
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2012-01-01

3.  Ear lobe crease: a marker of coronary artery disease?

Authors:  Aris P Agouridis; Moses S Elisaf; Devaki R Nair; Dimitri P Mikhailidis
Journal:  Arch Med Sci       Date:  2015-12-11       Impact factor: 3.318

4.  A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign.

Authors:  Aung Naing Lin; Kyawzaw Lin; Htoo Kyaw; Joseph Abboud
Journal:  Cureus       Date:  2018-01-17

5.  Diagonal earlobe crease and long-term survival after myocardial infarction.

Authors:  Christian Thilo; Christine Meisinger; Margit Heier; Wolfgang von Scheidt; Inge Kirchberger
Journal:  BMC Cardiovasc Disord       Date:  2021-12-16       Impact factor: 2.298

6.  The Histological Basis of Frank's Sign.

Authors:  George S Stoyanov; Deyan Dzhenkov; Lilyana Petkova; Nikolay Sapundzhiev; Svetoslav Georgiev
Journal:  Head Neck Pathol       Date:  2020-07-25

7.  Predictive value of auricular diagnosis on coronary heart disease.

Authors:  Lorna Kwai-Ping Suen; Yuk-Kong Lau; Hok-Cheung Ma; Kam-Wai Lai; Eleanor Holroyd
Journal:  Evid Based Complement Alternat Med       Date:  2012-12-24       Impact factor: 2.629

8.  Diagonal earlobe crease and coronary artery disease in a Chinese population.

Authors:  Xing-Li Wu; Ding-You Yang; Yu-Sheng Zhao; Wen-Hui Chai; Ming-Lei Jin
Journal:  BMC Cardiovasc Disord       Date:  2014-04-04       Impact factor: 2.298

9.  Did Dumbo suffer a heart attack? independent association between earlobe crease and cardiovascular disease.

Authors:  Marta Aligisakis; Pedro Marques-Vidal; Idris Guessous; Peter Vollenweider
Journal:  BMC Cardiovasc Disord       Date:  2016-01-20       Impact factor: 2.298

10.  The Association between Earlobe Crease (Frank's Sign) and Abnormal Ankle-Brachial Index Determination Is Related to Age: A Population-Based Study.

Authors:  Oscar H Del Brutto; Robertino M Mera; Aldo F Costa; Mauricio Zambrano; Mark J Sedler
Journal:  Int J Vasc Med       Date:  2018-09-02
  10 in total

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