Literature DB >> 1403685

Oxidative decarboxylation of naproxen.

F Boscá1, R Martínez-Máñez, M A Miranda, J Primo, J Soto, L Vañó.   

Abstract

The decarboxylation of naproxen (1H) and its salt (1-) was achieved by means of chemical [Ce(IV) or S2O8(2-)] and electrochemical oxidation. The product patterns were compatible with mechanisms involving single-electron transfer from the pi-system or the carboxylate moiety. The results are discussed in connection with the involvement of electron-transfer processes in the reported phototoxicity of naproxen.

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Year:  1992        PMID: 1403685     DOI: 10.1002/jps.2600810519

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  2 in total

1.  Chemiluminescence of the reaction system Ce(IV)-non-steroidal anti-inflammatory drugs containing europium(III) ions and its application to the determination of naproxen in pharmaceutical preparations and urine.

Authors:  Małgorzata Kaczmarek
Journal:  J Fluoresc       Date:  2011-07-13       Impact factor: 2.217

2.  Unified Total Synthesis of Pyrroloazocine Indole Alkaloids Sheds Light on Their Biosynthetic Relationship.

Authors:  Fedor M Miloserdov; Mariia S Kirillova; Michael E Muratore; Antonio M Echavarren
Journal:  J Am Chem Soc       Date:  2018-02-22       Impact factor: 15.419

  2 in total

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