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Literature DB >> 14035887

Iontophoretic release of adrenaline, noradrenaline and 5-hydroxytryptamine from micropipettes.

Abstract

Estimations have been made of the amounts of adrenaline, noradrenaline and 5-hydroxytryptamine released by iontophoresis from micropipettes. In most experiments, the amount released was linearly related to the total electrical charge, but the transport numbers for different pipettes, filled with samples of the same solutions of adrenaline or of noradrenaline, varied substantially. Two pipettes containing noradrenaline failed to release any appreciable amounts of the drug. The transport number of 5-hydroxytryptamine was relatively constant (mean, 0.14).

Entities: Chemical

Keywords: EPINEPHRINE; IONTOPHORESIS; NOREPINEPHRINE; SEROUS MEMBRANE

Mesh：

Substances：

Year: 1963 PMID： 14035887 PMCID： PMC1703820 DOI： 10.1111/j.1476-5381.1963.tb01485.x

Source DB: PubMed Journal: Br J Pharmacol Chemother ISSN： 0366-0826

7 in total

1. Excitaion and inhibition of brain-stem neurones by noradrenaline and acetylcholine.

Authors: P B BRADLEY; J H WOLSTENCROFT
Journal: Nature Date: 1962-12-01 Impact factor: 49.962

2. Iontophoretic studies of neurones in the mammalian cerebral cortex.

Authors: K KRNJEVIC; J W PHILLIS
Journal: J Physiol Date: 1963-02 Impact factor: 5.182

3. Determination of iontophoretic release of acetylcholine from micropipettes.

Authors: K KRNJEVIC; J F MITCHELL; J C SZERB
Journal: J Physiol Date: 1963-03 Impact factor: 5.182

4. Pharmacological studies upon neurones of the lateral geniculate nucleus of the cat.

Authors: D R CURTIS; R DAVIS
Journal: Br J Pharmacol Chemother Date: 1962-04

5. Fluorescence characteristics of 5-hydroxytryptamine (serotonin).

Authors: S UDENFRIEND; D F BOGDANSKI; H WEISSBACH
Journal: Science Date: 1955-11-18 Impact factor: 47.728

6. Actions of certain amines on cerebral cortical neurones.

Authors: K KRNJEVIC; J W PHILLIS
Journal: Br J Pharmacol Chemother Date: 1963-06

7. Noradrenaline content in the heart and spleen of the mouse under normal conditions and after administration of some drugs.

Authors: D F SHARMAN; S VANOV; M VOGT
Journal: Br J Pharmacol Chemother Date: 1962-12

7 in total

9 in total

1. Kinetics of the release of noradrenaline from micropipettes: interaction between ejecting and retaining currents.

Authors: C M Bradshaw; M H Roberts; E Szabadi
Journal: Br J Pharmacol Date: 1973-12 Impact factor: 8.739

2. Iontophoretic release of acetylcholine, noradrenaline, 5-hydroxytryptamine and D-lysergic acid diethylamide from micropipettes.

Authors: P B Bradley; J M Candy
Journal: Br J Pharmacol Date: 1970-10 Impact factor: 8.739

7. Localization of beta adrenergic receptors, and effects of noradrenaline and cyclic nucleotides on action potentials, ionic currents and tension in mammalian cardiac muscle.

Authors: H Reuter
Journal: J Physiol Date: 1974-10 Impact factor: 5.182

8. The inhibitory action of monoamines on lateral geniculate neurones.

Authors: J W Phillis; A K Tebècis; D H York
Journal: J Physiol Date: 1967-06 Impact factor: 5.182

Review 9. Improved techniques for examining rapid dopamine signaling with iontophoresis.

Authors: Natalie Rios Herr; Robert Mark Wightman
Journal: Front Biosci (Elite Ed) Date: 2013-01-01