Literature DB >> 1402968

The effect of immunosuppression on the development of cerebral oedema in an experimental model of intracerebral haemorrhage: whole body and regional irradiation.

P J Kane1, P Modha, R D Strachan, S Cook, I R Chambers, C B Clayton, A D Mendelow.   

Abstract

The oedema which forms around an intracerebral haemorrhage has a complex aetiology. The immune response may have a role in its formation. There is clinical and experimental evidence that circulating leucocytes and platelets may mediate oedema formation. Global depletion of circulating leucocytes and platelets by whole body irradiation in a rodent model of intracerebral haemorrhage was found to confer protection against both ischaemia and oedema formation. This was not a direct effect of irradiation of the brain. The possible mechanisms for this protection are discussed.

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Year:  1992        PMID： 1402968      PMCID： PMC1015102          DOI： 10.1136/jnnp.55.9.781

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN： 0022-3050            Impact factor:   10.154


  33 in total

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2.  Experimental intracerebral hemorrhage: early removal of a spontaneous mass lesion improves late outcome.

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Journal:  Neurosurgery       Date:  1990-11       Impact factor: 4.654

3.  Do leukocytes have a role in the cerebral no-reflow phenomenon?

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Journal:  J Neurol Neurosurg Psychiatry       Date:  1989-04       Impact factor: 10.154

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Journal:  Stroke       Date:  1985 Mar-Apr       Impact factor: 7.914

5.  Platelet-activating factor and progressive brain damage following focal brain injury.

Authors:  K U Frerichs; P J Lindsberg; J M Hallenbeck; G Z Feuerstein
Journal:  J Neurosurg       Date:  1990-08       Impact factor: 5.115

6.  The determination of brain water content: microgravimetry versus drying-weighing method.

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Journal:  J Neurosurg       Date:  1982-07       Impact factor: 5.115

7.  Midazolam and fentanyl-fluanisone: assessment of anaesthetic effects in laboratory rodents and rabbits.

Authors:  P A Flecknell; M Mitchell
Journal:  Lab Anim       Date:  1984-04       Impact factor: 2.471

8.  Cerebral blood flow and edema following carotid occlusion in the gerbil.

Authors:  A Crockard; F Iannotti; A T Hunstock; R D Smith; R J Harris; L Symon
Journal:  Stroke       Date:  1980 Sep-Oct       Impact factor: 7.914

Review 9.  H2 clearance measurement of blood flow: a review of technique and polarographic principles.

Authors:  W Young
Journal:  Stroke       Date:  1980 Sep-Oct       Impact factor: 7.914

10.  Polymorphonuclear leukocyte accumulation in brain regions with low blood flow during the early postischemic period.

Authors:  J M Hallenbeck; A J Dutka; T Tanishima; P M Kochanek; K K Kumaroo; C B Thompson; T P Obrenovitch; T J Contreras
Journal:  Stroke       Date:  1986 Mar-Apr       Impact factor: 7.914
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  6 in total

1.  Neutrophil depletion diminishes monocyte infiltration and improves functional outcome after experimental intracerebral hemorrhage.

Authors:  Lauren H Sansing; Tajie H Harris; Scott E Kasner; Christopher A Hunter; Katalin Kariko
Journal:  Acta Neurochir Suppl       Date:  2011

Review 2.  Preclinical and clinical research on inflammation after intracerebral hemorrhage.

Authors:  Jian Wang
Journal:  Prog Neurobiol       Date:  2010-08-14       Impact factor: 11.685

3.  Proteasome Inhibitor Reduces Astrocytic iNOS Expression and Functional Deficit after Experimental Intracerebral Hemorrhage in Rats.

Authors:  Fahmi M Al-Senani; Xiurong Zhao; James C Grotta; Ali Shirzadi; Roger Strong; Jaroslaw Aronowski
Journal:  Transl Stroke Res       Date:  2011-10-19       Impact factor: 6.829

4.  Gr1+ Macrophages and Dendritic Cells Dominate the Inflammatory Infiltrate 12 Hours After Experimental Intracerebral Hemorrhage.

Authors:  Matthew D Hammond; Youxi Ai; Lauren H Sansing
Journal:  Transl Stroke Res       Date:  2012-07       Impact factor: 6.829

5.  Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage.

Authors:  William B Rolland; Tim Lekic; Paul R Krafft; Yu Hasegawa; Orhan Altay; Richard Hartman; Robert Ostrowski; Anatol Manaenko; Jiping Tang; John H Zhang
Journal:  Exp Neurol       Date:  2012-12-21       Impact factor: 5.330

Review 6.  Stages of the Inflammatory Response in Pathology and Tissue Repair after Intracerebral Hemorrhage.

Authors:  Michael H Askenase; Lauren H Sansing
Journal:  Semin Neurol       Date:  2016-05-23       Impact factor: 3.420
  6 in total

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