Literature DB >> 14028398

Homology test between the nucleic acid of an RNA virus and the DNA in the host cell.

R H DOI, S SPIEGELMAN.   

Abstract

Deoxyribonucleic acid in the host cell does not contain a sequence complementary to the nucleic acid of an RNA virus. Specific formation of hybridbetween deoxyribonucleic acid and ribonucleic acid was used as a detecting device. The test was internally controlled and sensitive enough to reveal complementary stretches in the DNA corresponding to 10 percent of the viral ribonucleic acid. The implications of the results for replication and transcription of RNA are discussed.

Entities:  

Keywords:  COLIPHAGES; DNA, BACTERIAL; ESCHERICHIA COLI; RNA, VIRAL

Mesh:

Substances:

Year:  1962        PMID: 14028398     DOI: 10.1126/science.138.3546.1270

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  15 in total

1.  REPLICATION OF VIRAL RNA, III. DOUBLE-STRANDED REPLICATIVE FORM OF MSW PHAGE RNA.

Authors:  C WEISSMANN; P BORST; R H BURDON; M A BILLETER; S OCHOA
Journal:  Proc Natl Acad Sci U S A       Date:  1964-04       Impact factor: 11.205

Review 2.  ENTEROVIRUS ENTRANCE INTO SPECIFIC HOST CELLS, AND SUBSEQUENT ALTERATIONS OF CELL PROTEIN AND NUCLEIC ACID SYNTHESIS.

Authors:  J J HOLLAND
Journal:  Bacteriol Rev       Date:  1964-03

3.  AN RNA "REPLICASE" INDUCED BY AND SELECTIVE FOR A VIRAL RNA: ISOLATION AND PROPERTIES.

Authors:  I HARUNA; K NOZU; Y OHTAKA; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-11       Impact factor: 11.205

4.  Conservation of a viral RNA genome during replication and translation.

Authors:  R H DOI; S SPIEGELMAN
Journal:  Proc Natl Acad Sci U S A       Date:  1963-03-15       Impact factor: 11.205

5.  Not beyond reasonable doubt: Howard Temin's provirus hypothesis revisited.

Authors:  Susie Fisher
Journal:  J Hist Biol       Date:  2010       Impact factor: 1.326

6.  What history tells us XXXIII. Molecular hybridization: a problematic tool for the study of differentiation and development (1960-1980).

Authors:  Michel Morange
Journal:  J Biosci       Date:  2014-03       Impact factor: 1.826

Review 7.  Towards an experimental analysis of molecular self-organization and precellular Darwinian evolution.

Authors:  B Küppers
Journal:  Naturwissenschaften       Date:  1979-05

8.  Determination of natural host taxonomy of RNA tumor viruses by molecular hybridization: application to RD-114, a candidate human virus.

Authors:  R M Ruprecht; N C Goodman; S Spiegelman
Journal:  Proc Natl Acad Sci U S A       Date:  1973-05       Impact factor: 11.205

9.  Effect of bacteriophage R17 infection on host-directed synthesis of ribosomal ribonucleates.

Authors:  J B Hudson; W Paranchych
Journal:  J Virol       Date:  1967-06       Impact factor: 5.103

Review 10.  Symposium on replication of viral nucleic acids. I. Formation and properties of a replicative intermediate in the biosynthesis of viral ribonucleic acid.

Authors:  R L Erikson; R M Franklin
Journal:  Bacteriol Rev       Date:  1966-06
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