Literature DB >> 1402819

Sequence comparison between the phosphoprotein mRNAs of human and bovine respiratory syncytial viruses identifies a divergent domain in the predicted protein.

S K Mallipeddi1, S K Samal.   

Abstract

The nucleotide and deduced amino acid sequences of the phosphoprotein (P) mRNA of bovine respiratory syncytial virus (BRSV) strain A51908 have been determined. The P mRNA is 860 nucleotides long with a single large open reading frame and the encoded polypeptide is 241 amino acids long. Comparison with the corresponding sequences of human respiratory syncytial virus (HRSV) subgroups A and B revealed 72 to 74% identity at the nucleotide level, and 81% at the amino acid level. The P protein contains a single divergent domain (37% amino acid identity) flanked by highly conserved domains (87% amino acid identity). The 3' end non-coding region is 47 nucleotides shorter than the corresponding region of HRSV. Comparison of the P mRNA sequences of two strains of BRSV (A51908 and FS-1) showed that there was extensive sequence identity at both the nucleotide (97%) and amino acid (97.9%) levels.

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Year:  1992        PMID： 1402819     DOI： 10.1099/0022-1317-73-9-2441

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  11 in total

1.  A single amino acid substitution in the phosphoprotein of respiratory syncytial virus confers thermosensitivity in a reconstituted RNA polymerase system.

Authors:  A C Marriott; S D Wilson; J S Randhawa; A J Easton
Journal:  J Virol       Date:  1999-06       Impact factor: 5.103

2.  Live-cell characterization and analysis of a clinical isolate of bovine respiratory syncytial virus, using molecular beacons.

Authors:  Philip Santangelo; Nitin Nitin; Leslie LaConte; Amelia Woolums; Gang Bao
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

3.  Molecular epidemiology of subgroup C avian pneumoviruses isolated in the United States and comparison with subgroup a and B viruses.

Authors:  Hyun-Jin Shin; Kjerstin T Cameron; Janet A Jacobs; Elizabeth A Turpin; David A Halvorson; Sagar M Goyal; Kakambi V Nagaraja; Mahesh C Kumar; Dale C Lauer; Bruce S Seal; M Kariuki Njenga
Journal:  J Clin Microbiol       Date:  2002-05       Impact factor: 5.948

Review 4.  Bovine respiratory syncytial virus (BRSV): a review.

Authors:  L E Larsen
Journal:  Acta Vet Scand       Date:  2000       Impact factor: 1.695

5.  Identification of temperature-sensitive mutations in the phosphoprotein of respiratory syncytial virus that are likely involved in its interaction with the nucleoprotein.

Authors:  Bin Lu; Robert Brazas; Chien-Hui Ma; Tina Kristoff; Xing Cheng; Hong Jin
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

6.  Casein kinase 2-mediated phosphorylation of respiratory syncytial virus phosphoprotein P is essential for the transcription elongation activity of the viral polymerase; phosphorylation by casein kinase 1 occurs mainly at Ser(215) and is without effect.

Authors:  L C Dupuy; S Dobson; V Bitko; S Barik
Journal:  J Virol       Date:  1999-10       Impact factor: 5.103

7.  Sequence of the phosphoprotein gene of pneumonia virus of mice: expression of multiple proteins from two overlapping reading frames.

Authors:  J Barr; P Chambers; P Harriott; C R Pringle; A J Easton
Journal:  J Virol       Date:  1994-08       Impact factor: 5.103

8.  Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter.

Authors:  U J Buchholz; S Finke; K K Conzelmann
Journal:  J Virol       Date:  1999-01       Impact factor: 5.103

Review 9.  Epidemiology, molecular epidemiology and evolution of bovine respiratory syncytial virus.

Authors:  Rosa Elena Sarmiento-Silva; Yuko Nakamura-Lopez; Gilberto Vaughan
Journal:  Viruses       Date:  2012-11-30       Impact factor: 5.048

10.  Vaccine safety and efficacy evaluation of a recombinant bovine respiratory syncytial virus (BRSV) with deletion of the SH gene and subunit vaccines based on recombinant human RSV proteins: N-nanorings, P and M2-1, in calves with maternal antibodies.

Authors:  Krister Blodörn; Sara Hägglund; Jenna Fix; Catherine Dubuquoy; Boby Makabi-Panzu; Michelle Thom; Per Karlsson; Jean-Louis Roque; Erika Karlstam; John Pringle; Jean-François Eléouët; Sabine Riffault; Geraldine Taylor; Jean François Valarcher
Journal:  PLoS One       Date:  2014-06-19       Impact factor: 3.240
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