| Literature DB >> 14026027 |
E DE ROBERTIS, L SALGANICOFF, L M ZIEHER, G RODRIGUEZ DE LORES ARNAIZ.
Abstract
Acetylcholine, cholinacetylase, and acetylcholinesterase were determined in three subfractions that resulted from the osmotic shock of the "mitochondrial" fraction of the rat brain. Acetylcholine and cholinacetylase were found concentrated in the subfraction that contained mainly synaptic vesicles and some membranes, whereas the larger proportion of the acetylcholinesterase was observed in the subfraction that contained torn nerve endings. These results support the idea that synaptic vesicles are the morphological units of acetylcholine within the synapse.Entities:
Keywords: ACETYLCHOLINE; CHOLINESTERASE; MITOCHONDRIA; NERVE ENDINGS; SYNAPSES
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Year: 1963 PMID： 14026027 DOI： 10.1126/science.140.3564.300
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728