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Literature DB >> 14016021

Tarichatoxin: isolation and purification.

Abstract

The potent neurotoxin occurring in the embryos of the California newt, Taricha torosa, has been obtained in crystalline form. With a lethal subcutaneous dose of approximately 0.14 micrograms for a 20-gram mouse, it is, along with saxitoxin and tetrodotoxin, one of the most toxic nonprotein substances known.

Entities: Chemical Species

Keywords: TOXINS AND ANTITOXINS

Mesh：

Substances：

Year: 1963 PMID： 14016021 DOI： 10.1126/science.140.3564.295

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

12 in total

1. Presence of tetrodotoxin and tetrodotoxin-producing bacteria in freshwater sediments.

Authors: H K Do; K Hamasaki; K Ohwada; U Simidu; T Noguchi; Y Shida; K Kogure
Journal: Appl Environ Microbiol Date: 1993-11 Impact factor: 4.792

2. Evolutionary history of a complex adaptation: tetrodotoxin resistance in salamanders.

Authors: Charles T Hanifin; William F Gilly
Journal: Evolution Date: 2014-12-16 Impact factor: 3.694

Review 3. Chemistry of animal venoms.

Authors: E Zlotkin
Journal: Experientia Date: 1973-12

4. [On tetrodotoxin, poison of globefishes].

Authors: K Tsuda
Journal: Naturwissenschaften Date: 1966-04

5. Parallel arms races between garter snakes and newts involving tetrodotoxin as the phenotypic interface of coevolution.

Authors: Edmund D Brodie; Chris R Feldman; Charles T Hanifin; Jeffrey E Motychak; Daniel G Mulcahy; Becky L Williams; Edmund D Brodie
Journal: J Chem Ecol Date: 2005-02 Impact factor: 2.626

Tarichatoxin: isolation and purification.

1. Presence of tetrodotoxin and tetrodotoxin-producing bacteria in freshwater sediments.

2. Evolutionary history of a complex adaptation: tetrodotoxin resistance in salamanders.

Review 3. Chemistry of animal venoms.

4. [On tetrodotoxin, poison of globefishes].

5. Parallel arms races between garter snakes and newts involving tetrodotoxin as the phenotypic interface of coevolution.

Review 6. The chemical and evolutionary ecology of tetrodotoxin (TTX) toxicity in terrestrial vertebrates.

7. Blockage of sodium conductance increase in lobster giant axon by tarichatoxin (tetrodotoxin).

8. Phenotypic mismatches reveal escape from arms-race coevolution.

Review 9. Tetrodotoxin-Producing Bacteria: Detection, Distribution and Migration of the Toxin in Aquatic Systems.

10. The Acute Toxicity of Tetrodotoxin and Tetrodotoxin⁻Saxitoxin Mixtures to Mice by Various Routes of Administration.