Literature DB >> 14008167

Protection of rats against adjuvant arthritis by bacterial lipoplysaccharides.

F D WOOD, C M PEARSON.   

Abstract

Lipopolysaccharides from both gram-negative and gram-positive bacteria in incomplete adjuvant caused rats to become resistant to mycobacterial (complete) adjuvant arthritis. Lipopolysaccharides h protected rats when they were administered in adjuvant did not protect when administered in saline. Mycobacterial wax D in saline was protective, while in adjuvant it produced arthritis. The degree of stimulation of a common tissue reaction may determine whether the result is protection or disease.

Entities:  

Keywords:  ARTHRITIS/experimental; BACTERIA/chemistry; LIPOPOLYSACCHARIDES/pharmacology

Mesh：

Substances：

Year:  1962        PMID： 14008167     DOI： 10.1126/science.137.3529.544

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  10 in total

1.  Passive transfer of unresponsiveness by lymph node cells. Studies on adjuvant disease.

Authors:  E M Eugui; R H Houssay
Journal:  Immunology       Date:  1975-04       Impact factor: 7.397

2.  Influence of decontamination on induction of arthritis in Lewis rats by cell wall fragments of Eubacterium aerofaciens. Arthropathic properties of indigenous anaerobic bacteria.

Authors:  J Kool; A J Severijnen; I S Klasen; M Y Gerrits-Boeye; M P Hazenberg
Journal:  Ann Rheum Dis       Date:  1992-04       Impact factor: 19.103

3.  Gut flora induces and maintains resistance against streptococcal cell wall-induced arthritis in F344 rats.

Authors:  M F van den Broek; M C van Bruggen; J P Koopman; M P Hazenberg; W B van den Berg
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330

4.  A major contributory cause of arthritis in adjuvant-inoculated rats: granulocytes.

Authors:  E M Glenn; B J Bowman; N A Rohloff; R J Seely
Journal:  Agents Actions       Date:  1977-07

5.  Immunosuppressive activity of BCG: effects of adjuvant disease, lymphocyte subpopulations, and homing of thoracic duct cells in rats.

Authors:  R I Sutherland; M A Spadaro-Antonelli; V J Lawrence; F Quagliata
Journal:  Infect Immun       Date:  1979-07       Impact factor: 3.441

6.  Suppression of adjuvant disease by bacterial extracellular products.

Authors:  F Quagliata; A Taranta
Journal:  Ann Rheum Dis       Date:  1972-11       Impact factor: 19.103

7.  Inhibition of adjuvant arthritis by protein antigens. I. Inhibitory capacities and dose relationships of different proteins.

Authors:  C M Pearson; F D Wood
Journal:  Immunology       Date:  1969-02       Impact factor: 7.397

8.  Effect of hepatic injury on adjuvant arthritis.

Authors:  R S Pinals
Journal:  Ann Rheum Dis       Date:  1973-09       Impact factor: 19.103

9.  Adjuvant experimental polyarthritis.

Authors:  H Zahiri; J Gagnon; R Ayotte; C A Laurin
Journal:  Can Med Assoc J       Date:  1969-09-06       Impact factor: 8.262

10.  The effect of endotoxin and endotoxin tolerance on inflammation induced by mycobacterial adjuvant.

Authors:  J T Rosenbaum; R B Mandell
Journal:  Yale J Biol Med       Date:  1983 Jul-Aug
  10 in total

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