Literature DB >> 14005543

Experimental morphine addiction: method for automatic intravenous injections in unrestrained rats.

J R WEEKS.   

Abstract

An operant behavioral study on morphine addiction utilized a self-injection technique for giving intravenous injections to relatively unrestrained rats. The rate of self-injection varied inversely with the dose. Morphine was a reinforcer that produced almost immediate satiation.

Entities:  

Keywords:  INJECTIONS, INTRAVENOUS/equipment and supplies; MORPHINE ADDICTION/experimental

Mesh：

Substances：

Year:  1962        PMID： 14005543     DOI： 10.1126/science.138.3537.143

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  116 in total

1.  The production of morphine tolerance and physical dependence by the oral route in the rat. A comparative study.

Authors:  V O Fuentes; W B Hunt; J Crossland
Journal:  Psychopharmacology (Berl)       Date:  1978-09-15       Impact factor: 4.530

2.  Cocaine can generate a stronger conditioned reinforcer than food despite being a weaker primary reinforcer.

Authors:  Brendan J Tunstall; David N Kearns
Journal:  Addict Biol       Date:  2014-11-03       Impact factor: 4.280

3.  Differentiating the rapid actions of cocaine.

Authors:  Roy A Wise; Eugene A Kiyatkin
Journal:  Nat Rev Neurosci       Date:  2011-06-02       Impact factor: 34.870

4.  MORPHINE SELF-ADMINISTRATION, FOOD-REINFORCED, AND AVOIDANCE BEHAVIORS IN RHESUS MONKEYS.

Authors:  T THOMPSON; C R SCHUSTER
Journal:  Psychopharmacologia       Date:  1964-01-07

5.  RELATIVE POTENCY OF CODEINE, METHADONE AND DIHYDROMORPHINONE TO MORPHINE IN SELF-MAINTAINED ADDICT RATS.

Authors:  R J COLLINS; J R WEEKS
Journal:  Naunyn Schmiedebergs Arch Exp Pathol Pharmakol       Date:  1965-01-08

6.  The influence of behavior analysis on the surgeon general's report, the health consequences of smoking: Nicotine addiction.

Authors:  J E Henningfield; S T Higgins
Journal:  Behav Anal       Date:  1989

Review 7.  Rational development of addiction pharmacotherapies: successes, failures, and prospects.

Authors:  R Christopher Pierce; Charles P O'Brien; Paul J Kenny; Louk J M J Vanderschuren
Journal:  Cold Spring Harb Perspect Med       Date:  2012-06       Impact factor: 6.915

8.  Effects of serotonergic manipulations on cocaine self-administration in rats.

Authors:  R Peltier; S Schenk
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

9.  Reinforcer interactions under concurrent schedules of food, water, and intravenous morphine.

Authors:  S I Dworkin; G F Guerin; N E Goeders; D R Cherek; J D Lane; J E Smith
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

10.  Hold-down as an alternative to unit dose in cocaine self-administration experiments: Characterization using a progressive ratio schedule.

Authors:  David C S Roberts; Benjamin A Zimmer
Journal:  Psychopharmacology (Berl)       Date:  2020-05-28       Impact factor: 4.530
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